ArticleNature2023
Remote neuronal activity drives glioma progression through SEMA4F.
Open access · greenAbstract read
In one paragraph
Article in Nature, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 115 papers.
0numbers the graph read from it
0cells of the map it votes in
115citing papers in PubMed
23.7field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
115 citing papers in PubMed, 159 citations in OpenAlex.
- Stroke drives glioma progression through the emergence of tumor-associated astrocytes with reduced CaNature cancer · 2026Article
- Glioma microenvironment: Cellular crosstalk, immunosuppression, and novel therapeutic perspectives.Chinese medical journal · 2026Review
- Levetiracetam therapeutically targets GABAergic synapses in diffuse midline glioma.Nature medicine · 2026Article
- Gliomas phenocopy an inborn error of metabolism to drive neuronal activity and tumor growth.Cell · 2026Article
- Glioblastoma recurrence: An NGS-centered seed-soil framework.Neoplasia (New York, N.Y.) · 2026Article
- Targeting the nervous system: Mechanistic insights into neuro-tumor communication and therapeutic opportunities.Acta pharmaceutica Sinica. B · 2026Review
- Uncovering the signaling networks of disseminated glioblastoma cells in vivo with INSIGHT.Nature communications · 2026Article
- Identifying a Csmd3Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
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- Attract to kill: Exploring the potential of motility trapping as a novel treatment strategy for high-grade gliomas.Neuro-oncology · 2026Review
- Glioma-Associated Microglia Augment Neuronal Hyper-Excitability in Glioma.Brain tumor research and treatment · 2026Review
- Imaging strategies for delineating glioma margins: Aiming at precise therapy.Fundamental research · 2026Review
- ATRX inactivation disrupts global chromatin state and topology to dysregulate neurodevelopmental pathways in glioma pathogenesis.Nucleic acids research · 2026Article
- Hp1bp3 loss links chromatin reorganization to metabolic vulnerability in glioma.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Predicting the region of tumor micro-infiltration in glioblastoma peritumoral edema using a multiparametric mri radiomics model.Radiation oncology (London, England) · 2026Article
- Emerging Perspectives on Adverse Childhood Experiences and Brain Cancer Immunotherapy.Cancers · 2026Article
- Transsynaptic tracing techniques to interrogate neuronal connectivity of glioblastomas.Nature protocols · 2026Review
- Neuro-glioma activity-dependent growth mechanisms: an actionable circuit from NLGN3-ADAM10 to AMPA synapses.Translational cancer research · 2026Review
- Nested pediatric low-grade glioma cerebral organoid avatars reveal glutamatergic neuron stromal growth dependency.Genes & development · 2026Article
- Review
55 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
24 authors at 3 institutions in 1 country.
Emmet Huang-HobbsThe Integrative Molecular and Biomedical Sciences Graduate Program, Baylor College of Medicine, Houston, TX, USA.ORCID 0000-0002-2071-2588
Yi-Ting ChengCenter for Cell and Gene Therapy, Baylor College of Medicine, Houston, TX, USA.ORCID 0000-0001-8288-0707
Yeunjung KoCenter for Cell and Gene Therapy, Baylor College of Medicine, Houston, TX, USA.
Estefania Luna-FigueroaCenter for Cell and Gene Therapy, Baylor College of Medicine, Houston, TX, USA.
Brittney LozziCenter for Cell and Gene Therapy, Baylor College of Medicine, Houston, TX, USA.
Kathryn R TaylorDepartment of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA.
Malcolm McDonaldCenter for Cell and Gene Therapy, Baylor College of Medicine, Houston, TX, USA.
Peihao HeCenter for Cell and Gene Therapy, Baylor College of Medicine, Houston, TX, USA.
Hsiao-Chi ChenCenter for Cell and Gene Therapy, Baylor College of Medicine, Houston, TX, USA.ORCID 0000-0002-7505-6119
Yuhui YangDepartment of Neurosurgery, Baylor College of Medicine, Houston, TX, USA.
Ehson MalekiCenter for Cell and Gene Therapy, Baylor College of Medicine, Houston, TX, USA.ORCID 0009-0006-3286-9394
Zhung-Fu LeeCenter for Cell and Gene Therapy, Baylor College of Medicine, Houston, TX, USA.
Sanjana MuraliCenter for Cell and Gene Therapy, Baylor College of Medicine, Houston, TX, USA.
Michael R WilliamsonCenter for Cell and Gene Therapy, Baylor College of Medicine, Houston, TX, USA.ORCID 0000-0002-8049-4463
Dongjoo ChoiCenter for Cell and Gene Therapy, Baylor College of Medicine, Houston, TX, USA.
Rachel CurryThe Integrative Molecular and Biomedical Sciences Graduate Program, Baylor College of Medicine, Houston, TX, USA.
James BayleyDepartment of Neurosurgery, Baylor College of Medicine, Houston, TX, USA.
Junsung WooCenter for Cell and Gene Therapy, Baylor College of Medicine, Houston, TX, USA.
Ali JalaliCenter for Cancer Neuroscience, Baylor College of Medicine, Houston, TX, USA.
Michelle MonjeDepartment of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA.ORCID 0000-0002-3547-237X
Jeffrey L NoebelsDepartment of Human and Molecular Genetics, Baylor College of Medicine, Houston, TX, USA.
Akdes Serin HarmanciCenter for Cancer Neuroscience, Baylor College of Medicine, Houston, TX, USA.
Ganesh RaoCenter for Cancer Neuroscience, Baylor College of Medicine, Houston, TX, USA.
Benjamin DeneenThe Integrative Molecular and Biomedical Sciences Graduate Program, Baylor College of Medicine, Houston, TX, USA. deneen@bcm.edu.ORCID 0000-0002-6335-1081
Baylor College of Medicine · USHoward Hughes Medical Institute · USStanford University · US
Funding
Tumor BiologyP30CA125123 · NCI · BAYLOR COLLEGE OF MEDICINE · PI Suzanne AW Fuqua · 2007 to 2026
$73.9MVISION RESEARCH CENTERP30EY002520 · NEI · BAYLOR COLLEGE OF MEDICINE · PI Samuel M Wu · 1985 to 2026
$14.8MPreclinical and Clincial OutcomesP50HD103555 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI Sandesh Chakravarthy Sreenath Nagamani, David Loren Nelson · 2020 to 2026
$9.9MTraining In Cell and Gene TherapyT32HL092332 · NHLBI · BAYLOR COLLEGE OF MEDICINE · PI MALCOLM K. BRENNER, Bruno Di Stefano · 2008 to 2026
$6.9MGlioma Circuitry: Bridging Systems Neuroscience and CancerDP1NS111132 · NINDS · STANFORD UNIVERSITY · PI MONJE-DEISSEROTH, MICHELLE · 2018 to 2022
$5.7MTranscriptional regulation of gliogenesis in the CNSR01NS071153 · NINDS · BAYLOR COLLEGE OF MEDICINE · PI DENEEN, BENJAMIN · 2010 to 2022
$5.0MIntegrative bioinformatics and functional characterization of oncogenic driver aberrations in cancerU01CA217842 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI DENEEN, BENJAMIN, MILLS, GORDON B. · 2017 to 2021
$3.6MMOLECULAR DISSECTION OF SEIZURE MICROENVIRONMENT IN MALIGNANT GLIOMAR01CA223388 · NCI · BAYLOR COLLEGE OF MEDICINE · PI DENEEN, BENJAMIN, NOEBELS, JEFFREY · 2018 to 2022
$3.5MNeuronal Regulation of Low-Grade GliomagenesisR01CA258384 · NCI · STANFORD UNIVERSITY · PI David H Gutmann, Michelle Monje-Deisseroth · 2022 to 2026
$3.1MMODELING MALIGNANT PROGRESSION IN GLIOMAR01NS094615 · NINDS · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI RAO, GANESH · 2016 to 2020
$1.8MCellular and Molecular Mechanisms of GBM InfiltrationR01NS124093 · NINDS · BAYLOR COLLEGE OF MEDICINE · PI Benjamin Deneen, Ganesh Rao · 2022 to 2026
$1.6MHigh Throughput Genomic Sequencer at BCM Core FacilityS10OD023469 · OD · BAYLOR COLLEGE OF MEDICINE · PI CHEN, RUI · 2017 to 2017
$600kNCI NIH HHS F31 CA243382NCI NIH HHS F31 CA265156NCI NIH HHS P30 CA125123NCI NIH HHS R01 CA223388NCI NIH HHS R01 CA258384NCI NIH HHS U01 CA217842NEI NIH HHS P30 EY002520NHLBI NIH HHS T32 HL092332NICHD NIH HHS P50 HD103555NIH HHS S10 OD023469NIH HHS S10 OD025240NINDS NIH HHS DP1 NS111132NINDS NIH HHS R01 NS071153NINDS NIH HHS R01 NS094615NINDS NIH HHS R01 NS124093
Abstract
The tumour microenvironment plays an essential role in malignancy, and neurons have emerged as a key component of the tumour microenvironment that promotes tumourigenesis across a host of cancers
Indexed as
Brain NeoplasmsCarcinogenesisGliomaNeuronsTumor MicroenvironmentAnimalsAxonsBrainCell Line, TumorCell ProliferationCell Transformation, NeoplasticCorpus CallosumDisease ProgressionGlioblastomaHumansMembrane ProteinsMembrane ProteinsNerve Tissue ProteinsSEMA4F protein, human
Identifiers
What Socratic holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.