Evidence map›Paper›PMID 37398072›Full record

ArticlebioRxiv : the preprint server for biology2024

Lipid bilayer strengthens the cooperative network of membrane proteins.

Shaima Muhammednazaar, Jiaqi Yao, Matthew R Necelis, Yein C Park, Zhongtian Shen, Michael D Bridges, Ruiqiong Guo, Nicole Swope, May S Rhee, Miyeon Kim and 6 more

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 1 country.

Shaima Muhammednazaar
Jiaqi Yao
Matthew R Necelis
Yein C Park
Zhongtian Shen
Michael D Bridges
Ruiqiong Guo
Nicole Swope
May S Rhee
Miyeon Kim
Kelly H Kim
Wayne L Hubbell
Linda Columbus
Seung-Gu Kang
Heedeok Hong
Michigan State University · USIBM Research - Thomas J. Watson Research Center · US

Funding

Mechanistic Understanding of Post-Translational Membrane Protein TargetingR35GM147522 · NIGMS · MICHIGAN STATE UNIVERSITY · PI Hyojin (Kelly) Kim · 2022 to 2026
$1.9M
Folding and degradation of membrane proteinsR35GM144146 · NIGMS · MICHIGAN STATE UNIVERSITY · PI Heedeok Hong · 2022 to 2026
$1.5M
Folding and degradation of membrane proteinsR01GM118685 · NIGMS · MICHIGAN STATE UNIVERSITY · PI HONG, HEEDEOK · 2016 to 2020
$1.5M
NIGMS NIH HHS R01 GM118685NIGMS NIH HHS R35 GM144146NIGMS NIH HHS R35 GM147522
6 · The paper itself

Abstract

Although membrane proteins fold and function in a lipid bilayer constituting cell membranes, their structure and functionality can be recapitulated in diverse amphiphilic assemblies whose compositions deviate from native membranes. It remains unclear how various hydrophobic environments can stabilize membrane proteins and whether lipids play any role therein. Here, using the evolutionary unrelated α-helical and β-barrel membrane proteins of

Identifiers

PMID37398072
PMCPMC10312574
OpenAlexW4378802245

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.