ArticleResearch square2023
Spatial proteomics reveals human microglial states shaped by anatomy and neuropathology.
Open access · greenAbstract readPreprint
In one paragraph
Article in Research square, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 18 citations in OpenAlex.
- Extracellular vesicles released from microglia after palmitate exposure impact brain function.Journal of neuroinflammation · 2024Article
Corrections and comments
- Updated by
Authors and funding
24 authors at 5 institutions in 2 countries.
Dunja MrdjenDepartment of Pathology, Stanford University, School of Medicine, Palo Alto 94304, CA, USA.
Meelad AmouzgarDepartment of Pathology, Stanford University, School of Medicine, Palo Alto 94304, CA, USA.
Bryan CannonDepartment of Pathology, Stanford University, School of Medicine, Palo Alto 94304, CA, USA.
Candace LiuDepartment of Pathology, Stanford University, School of Medicine, Palo Alto 94304, CA, USA.
Angie SpenceDepartment of Pathology, Stanford University, School of Medicine, Palo Alto 94304, CA, USA.
Erin McCaffreyDepartment of Pathology, Stanford University, School of Medicine, Palo Alto 94304, CA, USA.ORCID 0000-0001-7241-1798
Anusha BharadwajDepartment of Pathology, Stanford University, School of Medicine, Palo Alto 94304, CA, USA.
Dmitry TebaykinDepartment of Pathology, Stanford University, School of Medicine, Palo Alto 94304, CA, USA.
Syed BukhariDepartment of Pathology, Stanford University, School of Medicine, Palo Alto 94304, CA, USA.
Felix J HartmannDepartment of Pathology, Stanford University, School of Medicine, Palo Alto 94304, CA, USA.
Adam KagelDepartment of Pathology, Stanford University, School of Medicine, Palo Alto 94304, CA, USA.
Kausalia VijayaragavanDepartment of Pathology, Stanford University, School of Medicine, Palo Alto 94304, CA, USA.
John Paul OliveriaDepartment of Pathology, Stanford University, School of Medicine, Palo Alto 94304, CA, USA.
Koya YakabiDepartment of Pathology, Stanford University, School of Medicine, Palo Alto 94304, CA, USA.
Geidy E SerranoBanner Sun Health Research Institute, Sun City, 85351, AZ, USA.
Maria M CorradaDepartment of Neurology, University of California, Irvine, 9269, CA, USA.
Claudia H KawasDepartment of Neurology, University of California, Irvine, 9269, CA, USA.
Christine CamachoDepartment of Pathology, Stanford University, School of Medicine, Palo Alto 94304, CA, USA.
Marc BosseDepartment of Pathology, Stanford University, School of Medicine, Palo Alto 94304, CA, USA.ORCID 0000-0003-4912-8059
Robert TibshiraniDepartment of Pathology, Stanford University, School of Medicine, Palo Alto 94304, CA, USA.
Thomas G BeachBanner Sun Health Research Institute, Sun City, 85351, AZ, USA.
Michael AngeloDepartment of Pathology, Stanford University, School of Medicine, Palo Alto 94304, CA, USA.ORCID 0000-0003-1531-5067
Thomas MontineDepartment of Pathology, Stanford University, School of Medicine, Palo Alto 94304, CA, USA.ORCID 0000-0002-1346-2728
Sean C BendallDepartment of Pathology, Stanford University, School of Medicine, Palo Alto 94304, CA, USA.ORCID 0000-0003-1341-2453
Stanford University · USStanford Medicine · USBanner Sun Health Research Institute · USUniversity of California, Irvine · USGerman Cancer Research Center · DE
Funding
Diversity Supplement to R01AG021055; Clinical, Imaging, and Pathological Studies in the Oldest Old: The 90+ StudyR01AG021055 · NIA · UNIVERSITY OF CALIFORNIA-IRVINE · PI CORRADA, MARIA, KAWAS, CLAUDIA H. · 2002 to 2024
$36.9MResearch Education ComponentP30AG019610 · NIA · SUN HEALTH RESEARCH INSTITUTE · PI REIMAN, ERIC MICHAEL · 2001 to 2020
$32.5MStanford Alzheimer's Disease Research CenterAdmin Supp: Developing iPSC models for AD and PDP30AG066515 · NIA · STANFORD UNIVERSITY · PI Lisa Goldman Rosas · 2020 to 2026
$29.0MThe Alzheimer's Disease Research Center at the University of California, IrvineP30AG066519 · NIA · UNIVERSITY OF CALIFORNIA-IRVINE · PI Mathew Mark Blurton-Jones · 2020 to 2026
$27.9MMOLECULAR &CELLULAR IMMUNOBIOLOGYT32AI007290 · NIAID · STANFORD UNIVERSITY · PI Sean Curtis Bendall, Olivia M Martinez · 1985 to 2026
$27.0MResearch Education ComponentP30AG072980 · NIA · BANNER HEALTH · PI ALIREZA ATRI · 2021 to 2026
$24.9MStanford Cancer Immune Monitoring and Analysis Center (CIMAC)U24CA224309 · NCI · STANFORD UNIVERSITY · PI Sean Curtis Bendall, Holden T. Maecker · 2017 to 2026
$19.9MProject 4: Novel reagent development to enable molecular characterizationU19AG065156 · NIA · UNIVERSITY OF WASHINGTON · PI TIAN, LU · 2020 to 2024
$15.9MThe Bone Marrow Multi-modal Imaging CoreU54HL165445 · NHLBI · STANFORD UNIVERSITY · PI ANGELO, ROBERT MICHAEL, BENDALL, SEAN CURTIS · 2022 to 2025
$5.9MMIRIAD - Multiplexed Imaging of Resilience In Alzheimers DiseaseR01AG057915 · NIA · STANFORD UNIVERSITY · PI ANGELO, ROBERT MICHAEL, BENDALL, SEAN CURTIS · 2017 to 2021
$4.5MThe Phenotypic Landscape of Cognitive Decline as Revealed by Next-Generation Multiplexed Ion Beam ImagingR01AG056287 · NIA · STANFORD UNIVERSITY · PI ANGELO, ROBERT MICHAEL, BENDALL, SEAN CURTIS · 2017 to 2021
$2.6MUncoupling Age- Versus Cognitive-Related Cellular Senescence in Alzheimer's DiseaseR01AG068279 · NIA · STANFORD UNIVERSITY · PI BENDALL, SEAN CURTIS · 2020 to 2024
$1.9MNCI NIH HHS U24 CA224309NHLBI NIH HHS U54 HL165445NIAID NIH HHS T32 AI007290NIA NIH HHS P30 AG019610NIA NIH HHS P30 AG066515NIA NIH HHS P30 AG066519NIA NIH HHS P30 AG072980NIA NIH HHS R01 AG021055NIA NIH HHS R01 AG056287NIA NIH HHS R01 AG057915NIA NIH HHS R01 AG068279NIA NIH HHS U19 AG065156
Abstract
Microglia are implicated in aging, neurodegeneration, and Alzheimer's disease (AD). Traditional, low-plex, imaging methods fall short of capturing
Identifiers
What Socratic holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.