Evidence map›Paper›PMID 37398562›Full record

ArticleToxicological research2023

Immunodysregulatory potentials of polyethylene or polytetrafluorethylene microplastics to mice subacutely exposed via intragastric intubation.

JiHun Jo, Manju Acharya, Pramod Bahadur K C, Anju Maharjan, DaEun Lee, Ravi Gautam, Jung-Taek Kwon, KilSoo Kim, ChangYul Kim, Yong Heo and 1 more

Abstract read
In one paragraph

Article in Toxicological research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

JiHun JoDepartment of Occupational Health, College of Bio and Medical Sciences, Daegu Catholic University, Gyeongsan, Republic of Korea.
Manju AcharyaDepartment of Occupational Health, College of Bio and Medical Sciences, Daegu Catholic University, Gyeongsan, Republic of Korea.
Pramod Bahadur K CDepartment of Toxicology, Graduate School of Daegu Catholic University, Gyeongsan, Republic of Korea.
Anju MaharjanDepartment of Occupational Health, College of Bio and Medical Sciences, Daegu Catholic University, Gyeongsan, Republic of Korea.
DaEun LeeDepartment of Occupational Health, College of Bio and Medical Sciences, Daegu Catholic University, Gyeongsan, Republic of Korea.
Ravi GautamDepartment of Occupational Health, College of Bio and Medical Sciences, Daegu Catholic University, Gyeongsan, Republic of Korea.
Jung-Taek KwonEnvironmental Health Research Department, National Institute of Environmental Research, Incheon, Republic of Korea.
KilSoo KimPreclinical Research Center, Daegu-Gyeongbuk Medical Innovation Foundation, Daegu, Republic of Korea.
ChangYul KimDepartment of Toxicology, Graduate School of Daegu Catholic University, Gyeongsan, Republic of Korea.
Yong HeoDepartment of Occupational Health, College of Bio and Medical Sciences, Daegu Catholic University, Gyeongsan, Republic of Korea.
HyoungAh KimDepartment of Preventive Medicine, College of Medicine, The Catholic University of Korea, 222 Banpo-daero, Seocho-gu, Seoul, 06591 Republic of Korea.ORCID 0000-0002-8805-3101

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microplastics (MPs) have been recently recognized as posing a risk to human health. The adverse health effects of MP exposure have been recently reported, especially via the oral exposure route. The present study investigated whether subacute (4 week) exposure to polyethylene (PE) or polytetrafluorethylene (PTFE) MPs via gastric intubation caused immunotoxicity. Two different sizes of PE MPs (6.2 or 27.2 μm) and PTFE MPs (6.0 or 30.5 μm) were administered to 6-week-old mice of both sexes at 0 (corn oil vehicle control), 500, 1000, or 2000 mg/kg/day (n = 4/group). No significant differences were observed between groups in the major thymic or splenic immune cell populations, including thymic CD4 Supplementary Information: The online version contains supplementary material available at 10.1007/s43188-023-00172-6.

Indexed as

ImmunotoxicityMicroplastic toxicityPolyethylenePolytetrafluorethyleneSubacute intragastric administration

Identifiers

PMID37398562
PMCPMC10313636

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.