ArticleThe Plant cell2023
Thermosensitive SUMOylation of TaHsfA1 defines a dynamic ON/OFF molecular switch for the heat stress response in wheat.
Article in The Plant cell, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed, 52 citations in OpenAlex.
- Genome-wide analysis of the HSF gene family in lily and functional characterization of LdHSFC1 under heat stress.Plant cell reports · 2026Article
- Harnessing genomics approaches for heat stress resilience in wheat: from discovery to deployment.Journal of experimental botany · 2026Review
- Principles and mechanisms of plant acclimation to heat stress.Nature reviews. Molecular cell biology · 2026Review
- Identifying heat shock-responsive lncRNAs in wheat during grain filling.BMC plant biology · 2026Article
- Epigenetic-epitranscriptomic crosstalk through TaHAG1-TaNSUN2 coordinates thermotolerance in wheat.Nature communications · 2026Article
- Integrating molecular networks and physiological adaptation for heat-resilient crops.Journal of integrative plant biology · 2026Review
- SUMOylation in plants: A versatile post-translational mechanism responding to environmental stresses.Journal of integrative plant biology · 2026Review
- Advances in CRISPR Plant Applications.International journal of molecular sciences · 2026Review
- Lily Transcription Factors LlPLATZ1 and LlMYB4 Orchestrate the Homeostasis of Heat Stress Responses via Antagonistic Regulation of LlHSF24.Plant biotechnology journal · 2026Article
- Divergent Regulatory Effects of Jasmonic Acid on Tomato Lycopene Biosynthesis Under Light and Dark Conditions.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Genome-wide identification of Hsf gene family in citrus and functional analysis of CsHsfA1a in heat stress response.Plant cell reports · 2026Article
- Investigations into genetic control of six spike traits with a focus on breeding for terminal heat stress tolerance in common wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- Review
- Genome-wide identification and expression analysis of the Small Ubiquitin-like Modifier (SUMO) gene family in Triticum aestivum L.BMC genomics · 2025Article
- Translational regulation plasticity shapes wheat grain adaptation to heat stress.Genome biology · 2025Article
- An ABF5b-HsfA2h/HsfC2a-NCED2b/POD4/HSP26 module integrates multiple signaling pathway to modulate heat stress tolerance in wheat.Plant biotechnology journal · 2025Article
- Heat stress response factor ZmHSF10 positively regulates heat tolerance in maize.BMC plant biology · 2025Article
- Two complementary NLRs from wild emmer wheat confer powdery mildew resistance.Nature communications · 2025Article
- Plants repress ROS1 expression to attenuate heat-induced transposon burst.Nature plants · 2025Article
- The 14-3-3 Protein OsGF14h Coordinates Brassinosteroid and Gibberellin Signaling to Regulate Plant Growth and Grain Yield in Rice.Rice (New York, N.Y.) · 2025Article
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Authors and funding
18 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dissecting genetic components in crop plants associated with heat stress (HS) sensing and adaptation will facilitate the design of modern crop varieties with improved thermotolerance. However, the molecular mechanisms underlying the ON/OFF switch controlling HS responses (HSRs) in wheat (Triticum aestivum) remain largely unknown. In this study, we focused on the molecular action of TaHsfA1, a class A heat shock transcription factor, in sensing dynamically changing HS signals and regulating HSRs. We show that the TaHsfA1 protein is modified by small ubiquitin-related modifier (SUMO) and that this modification is essential for the full transcriptional activation activity of TaHsfA1 in triggering downstream gene expression. During sustained heat exposure, the SUMOylation of TaHsfA1 is suppressed, which partially reduces TaHsfA1 protein activity, thereby reducing the intensity of downstream HSRs. In addition, we demonstrate that TaHsfA1 interacts with the histone acetyltransferase TaHAG1 in a thermosensitive manner. Together, our findings emphasize the importance of TaHsfA1 in thermotolerance in wheat. In addition, they define a highly dynamic SUMOylation-dependent "ON/OFF" molecular switch that senses temperature signals and contributes to thermotolerance in crops.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.