Evidence map›Paper›PMID 37402250›Full record

SynthesisSchizophrenia bulletin2023

Incidence and Persistence of Psychotic Experiences in the General Population: Systematic Review and Meta-Analysis.

Lorna Staines, Colm Healy, Felim Murphy, Jonah Byrne, Jennifer Murphy, Ian Kelleher, David Cotter, Mary Cannon

Open access · hybridAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Schizophrenia bulletin, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
15.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it, 61 citations in OpenAlex.

  1. Pooled it
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  9. Sex differences in the effect of childhood adversity and coping strategies on psychosis expression: A TwinssCan study.European psychiatry : the journal of the Association of European Psychiatrists · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Lorna StainesDepartment of Psychiatry, Royal College of Surgeons in Ireland, Dublin 2, Ireland.
Colm HealyDepartment of Psychiatry, Royal College of Surgeons in Ireland, Dublin 2, Ireland.ORCID 0000-0001-7974-1861
Felim MurphyDepartment of Psychiatry, Royal College of Surgeons in Ireland, Dublin 2, Ireland.
Jonah ByrneDepartment of Psychiatry, Royal College of Surgeons in Ireland, Dublin 2, Ireland.ORCID 0000-0002-7046-0630
Jennifer MurphyDepartment of Psychiatry, Royal College of Surgeons in Ireland, Dublin 2, Ireland.
Ian KelleherDivision of Psychiatry, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, EH10 5HF, UK.
David CotterDepartment of Psychiatry, Royal College of Surgeons in Ireland, Dublin 2, Ireland.
Mary CannonDepartment of Psychiatry, Royal College of Surgeons in Ireland, Dublin 2, Ireland.
Royal College of Surgeons in Ireland · IEUniversity of Edinburgh · GB

Funding

European Research Council 724809Health Research Board ILP-PHR-2019-009Science Foundation Ireland 16/RC/3948415Wellcome Trust 220438Z/20/Z
6 · The paper itself

Abstract

background and hypothesisPsychotic experiences (PEs) are associated with increased risk for mental disorders, in particular persistent PEs. PEs therefore might be useful within intervention research. We sought to systematically determine the incidence and persistence of PEs in the general population. STUDY

designA double-blind search of databases (Embase, Pubmed PMC, Psychinfo, Medline, and Web of Science) from inception to January 2023 and data extraction, were conducted. Study quality was assessed using the NIH assessment tool. Random effects models were conducted to calculate pooled incidence rate per person-year and proportion of persistent PEs per year. Age and study design were all examined using subgroup analyses. Demographic, risk factors, and outcomes for incidence and persistence of PEs were reported in a narrative synthesis. STUDY

resultsUsing a double-blind screening method for abstract (k = 5763) and full text (k = 250) were screened. In total 91 samples from 71 studies were included, of which 39 were included in a meta-analysis (incidence: k = 17, n = 56 089; persistence: k = 22, n = 81 847). Incidence rate was 0.023 per person-year (95% CI [0.0129;0.0322]). That is, for every 100 people, 2 reported first onset PEs in a year. This was highest in adolescence at 5 per 100(13-17 years). The pooled persistence rate for PEs was 31.0% (95% CI [26.65,35.35]) This was highest in adolescence at 35.8%. Cannabis was particularly associated with incidence of PEs, and persistence of PEs were associated with multiple mental disorders.

conclusionsEach year incidence of PEs is 2 of every 100 people, and persists each year in 31% of cases, this risk is highest in adolescents.

Indexed as

Mental DisordersPsychotic DisordersAdolescentHumansIncidenceRandomized Controlled Trials as TopicRisk Factors

Identifiers

PMID37402250
PMCPMC10318880
OpenAlexW4366204521

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.