Evidence map›Paper›PMID 37406429›Full record

ReviewCurrent opinion in genetics & development2023

Adipose 'neighborhoods' collaborate to maintain metabolic health.

Susan K Fried

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in genetics & development, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Mechanisms by which obesity regulates inflammation and anti-tumor immunity in cancer.Biochemical and biophysical research communications · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Susan K FriedDiabetes, Obesity and Metabolism Institute, Icahn School of Medicine at Mount Sinai, One Gustave Levy Place, Box 1152, New York, NY 10029, USA. Electronic address: susan.fried@mssm.edu.
Icahn School of Medicine at Mount Sinai · US

Funding

Mechanisms regulating functional heterogeneity of subcutaneous adipose tissues in womenR01DK121547 · NIDDK · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI FRIED, SUSAN K · 2019 to 2023
$3.5M
Glucocorticoids & Adipocyte Function in Human ObesityR01DK080448 · NIDDK · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI FRIED, SUSAN K · 2009 to 2018
$3.4M
NIDDK NIH HHS R01 DK080448NIDDK NIH HHS R01 DK121547
6 · The paper itself

Abstract

Body fat is stored in anatomically distinct adipose depots that vary in their cell composition and play specialized roles in systemic metabolic homeostasis via secreted products. Their local effects on nearby tissues (e.g. the gut and visceral adipose tissues) are increasingly recognized and this local crosstalk is being elucidated. The major subcutaneous fat depots, abdominal and gluteal-femoral, exert opposite effects on the risk of metabolic disease. The pace of research into developmental, sex, and genetic determinants of human adipose depot growth and function is rapidly accelerating, providing insight into the pathogenesis of metabolic dysfunction in persons with obesity.

Indexed as

Adipose TissueObesityAdiposityHumansIntra-Abdominal FatSubcutaneous Fat

Identifiers

PMID37406429
PMCPMC10867982
OpenAlexW4383031888

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.