Evidence map›Paper›PMID 37408696›Full record

ArticleMaterials today. Bio2023

Treatment with FAP-targeted zinc ferrite nanoparticles for rheumatoid arthritis by inducing endoplasmic reticulum stress and mitochondrial damage.

Weizhong Qi, Li Jin, Cuixi Wu, Hao Liao, Mengdi Zhang, Zhaohua Zhu, Weiyu Han, Qiyue Chen, Changhai Ding

Abstract read
In one paragraph

Article in Materials today. Bio, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
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  7. Article
  8. Article
  9. Review
  10. Review
  11. Trace Elements-Role in Joint Function and Impact on Joint Diseases.International journal of molecular sciences · 2025
    Review
  12. TIGAR Suppresses ER Stress-Induced Neuronal Injury through Targeting ATF4 Signaling in Cerebral Ischemia/Reperfusion.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  13. Review
  14. Review
  15. Review
  16. Review
  17. Review
  18. Stimuli-Responsive Nanoplatforms for Precision Intervention in Rheumatoid Arthritis.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Weizhong QiClinical Research Centre, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282, China.
Li JinRheumatology and Clinical Immunology, ZhuJiang Hospital, Southern Medical University, Guangzhou, 510282, China.
Cuixi WuClinical Research Centre, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282, China.
Hao LiaoCentre of Orthopedics, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282, China.
Mengdi ZhangClinical Research Centre, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282, China.
Zhaohua ZhuClinical Research Centre, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282, China.
Weiyu HanClinical Research Centre, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282, China.
Qiyue ChenStomatological Hospital, Southern Medical University, Guangzhou, 510282, China.
Changhai DingClinical Research Centre, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rheumatoid arthritis (RA) is a common chronic inflammatory disease characterized by the proliferation of fibroblast-like synoviocytes (FLS), pannus development, cartilage, and bone degradation, and, eventually, loss of joint function. Fibroblast activating protein (FAP) is a particular product of activated FLS and is highly prevalent in RA-derived fibroblast-like synoviocytes (RA-FLS). In this study, zinc ferrite nanoparticles (ZF-NPs) were engineered to target FAP

Indexed as

Endoplasmic reticulum stressMagnetic hyperthermiaMitochondrial damageRheumatoid arthritisZinc ferrite nanoparticles

Identifiers

PMID37408696
PMCPMC10319325

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.