ArticlePsychological medicine2023
Prevalence of cognitive impairments and strengths in the early course of psychosis and depression.
Article in Psychological medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.
- Effects of working memory training on depressive symptoms: a systematic review and meta-analysis of randomized controlled trials.Translational psychiatry · 2026Pooled it
- Feasibility and Acceptability of Providing Cognitive Remediation in a Large USA System of Coordinated Specialty Care for Early Psychosis.Early intervention in psychiatry · 2025Trial
- Disentangling white matter correlates of symptom severity and general impairment in early psychosis.Molecular psychiatry · 2026Article
- No Cognitive Scarring Over 20 Years in Recurrent Depression: Bidirectionality of Cognitive Functioning and Depression.Clinical psychology in Europe · 2026Article
- Whole brain grey matter synaptic terminal density, age and intellectual functioning in schizophrenia: an in vivo [Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Article
- Online search interest in major depressive disorder: Infodemiology study using the most visited search engine in Japan.PloS one · 2026Observational
- Cognitive assessment in the Accelerating Medicines Partnership® Schizophrenia Program: harmonization priorities and strategies in a diverse international sample.Schizophrenia (Heidelberg, Germany) · 2025Article
- Exploring the Implementation of Cognitive Screening in First-Episode Psychosis Settings: The CogScreen Implementation Study.Early intervention in psychiatry · 2025Article
- Relationship between leisure activity and depression in Chinese older adults: chain mediating effect of diet and cognition.BMC geriatrics · 2025Article
- The relationship between cognitive and global function in patients with schizophrenia and mood disorders: a transdiagnostic network analysis.Frontiers in psychiatry · 2025Article
- Validating cognitive screening in young people with first-episode psychosis: The CogScreen protocol.Early intervention in psychiatry · 2025Article
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Authors and funding
31 authors at 15 institutions in 7 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundStudies investigating cognitive impairments in psychosis and depression have typically compared the average performance of the clinical group against healthy controls (HC), and do not report on the actual
methodsA comprehensive cognitive test battery comprising 12 tests was completed by 1286 individuals aged 15-41 (mean age 25.07, s.d. 5.88) from the PRONIA study at baseline: HC (
resultsImpairment in at least two cognitive tests was as follows: ROP (88.3% moderately, 45.1% severely impaired), CHR (71.2% moderately, 22.4% severely impaired), ROD (61.6% moderately, 16.2% severely impaired). Across clinical groups, impairments were most prevalent in tests of working memory, processing speed, and verbal learning. Above average performance (>1 s.d.) in at least two tests was present for 40.5% ROD, 36.1% CHR, 16.1% ROP, and was >2 SDs in 1.8% ROD, 1.4% CHR, and 0% ROP.
conclusionsThese findings suggest that interventions should be tailored to the individual, with working memory, processing speed, and verbal learning likely to be important transdiagnostic targets.
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