ArticleScience (New York, N.Y.)2023
Structural basis of gRNA stabilization and mRNA recognition in trypanosomal RNA editing.
Open access · greenAbstract read
In one paragraph
Article in Science (New York, N.Y.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 17 citations in OpenAlex.
- Conserved and divergent mitochondrial assemblies in kinetoplastid parasites.Molecular cell · 2026Article
- Article
- Nature Counts to Three: Universal Mg-Pinch Motif Polarizes the Cleaved Bond in NTP-Processing Enzymes.Journal of the American Chemical Society · 2026Article
- Leishmania major virulence attenuation in vitro: An old conundrum revisited in the omics era.PLoS neglected tropical diseases · 2026Article
- KREPA6 functions in RNA editing catalytic complex structural organization and gRNA utilization in Trypanosoma brucei.Nucleic acids research · 2026Article
- Nanoscaled, Fully Automated Hydrogen/Deuterium Exchange for Analysis of Macromolecular Assemblies Reaching the MDa Scale.Molecular & cellular proteomics : MCP · 2026Article
- Kinetoplast DNA structure, RNA editing patterns and small respiratory Complex I in Trypanosoma musculi.Communications biology · 2025Article
- FASTK post-transcriptional regulators - a 'FAST-tracK' in mitochondrial gene expression.Biochemical Society transactions · 2025Review
- Comparative mitochondrial genome and transcriptome analyses reveal strain-specific features of RNA editing in Trypanosoma brucei.Nucleic acids research · 2025Article
- DRBD18 acts as a transcript-specific RNA editing auxiliary factor inRNA (New York, N.Y.) · 2025Article
- KRBP72 facilitates ATPase-dependent editing progression through a structural roadblock in mitochondrial A6 mRNA.Nucleic acids research · 2025Article
- KREH2 helicase represses ND7 mRNA editing in procyclic-stage Trypanosoma brucei by opposite modulation of canonical and 'moonlighting' gRNA utilization creating a proposed mRNA structure.Nucleic acids research · 2024Article
- Review
- RESC14 and RESC8 cooperate to mediate RESC function and dynamics during trypanosome RNA editing.Nucleic acids research · 2024Article
- Blastocrithidia nonstop mitochondrial genome and its expression are remarkably insulated from nuclear codon reassignment.Nucleic acids research · 2024Article
- Prioritization of Trypanosoma brucei editosome protein interactions interfaces at residue resolution through proteome-scale network analysis.BMC molecular and cell biology · 2024Article
- Detection of Developmental Asexual Stage-Specific RNA Editing Events inMicroorganisms · 2024Article
- Deep mutational scanning of the RNase III-like domain inFrontiers in cellular and infection microbiology · 2024Article
- RNA editing catalytic complexes edit multiple mRNA sites non-processively in Trypanosoma brucei.Molecular and biochemical parasitology · 2023Article
- Unravelling the genetic heart-brain connection using MRI.Nature reviews. Cardiology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors at 5 institutions in 2 countries.
Shiheng Liu *Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, CA, USA.ORCID 0000-0002-0561-1981
Hong Wang *Department of Molecular and Cell Biology, Boston University Medical Campus, Boston, MA, USA.ORCID 0000-0002-5767-2882
Xiaorun LiDepartment of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, CA, USA.ORCID 0000-0003-2100-7554
Fan ZhangSchool of Life Science and Technology, ShanghaiTech University, Shanghai, China.ORCID 0000-0002-2858-0698
Jane K J LeeDepartment of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, CA, USA.ORCID 0000-0001-7735-7647
Zihang LiDepartment of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, CA, USA.ORCID 0000-0002-4625-9283
Clinton YuDepartment of Physiology and Biophysics, University of California, Irvine, CA, USA.ORCID 0000-0002-2931-5474
Jason J HuDepartment of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, CA, USA.ORCID 0000-0002-1103-2177
Xiaojing ZhaoSchool of Life Science and Technology, ShanghaiTech University, Shanghai, China.
Takuma SuematsuDepartment of Molecular and Cell Biology, Boston University Medical Campus, Boston, MA, USA.ORCID 0000-0003-1430-6580
Ana L Alvarez-CabreraDepartment of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, CA, USA.ORCID 0000-0001-7186-9393
Qiushi LiuDepartment of Molecular and Cell Biology, Boston University Medical Campus, Boston, MA, USA.
Liye ZhangSchool of Life Science and Technology, ShanghaiTech University, Shanghai, China.ORCID 0000-0003-2104-6828
Lan HuangDepartment of Physiology and Biophysics, University of California, Irvine, CA, USA.ORCID 0000-0002-3140-4687
Inna AphasizhevaDepartment of Molecular and Cell Biology, Boston University Medical Campus, Boston, MA, USA.ORCID 0000-0003-2695-2950
Ruslan AphasizhevDepartment of Molecular and Cell Biology, Boston University Medical Campus, Boston, MA, USA.ORCID 0000-0002-4595-6618
Z Hong ZhouDepartment of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, CA, USA.ORCID 0000-0002-8373-4717
California NanoSystems Institute · USBoston Medical Center · USShanghaiTech University · CNUniversity of California, Irvine · USBoston University · US
Funding
Proteomics of the Proteasome Interacting NetworksR01GM074830 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI HUANG, LAN · 2005 to 2022
$6.1MGuide RNA Binding ComplexR01AI101057 · NIAID · UNIVERSITY OF CALIFORNIA-IRVINE · PI Ruslan Afasizhev · 2012 to 2026
$6.0MHigh-Resolution CryoEM Reconstruction of Large ComplexesR01GM071940 · NIGMS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI ZHOU, Z HONG · 2006 to 2025
$5.0MREPEAT-CONTAINING RNA BINDING PROTEINS OF TRYPANOSOMESR01AI113157 · NIAID · BOSTON UNIVERSITY MEDICAL CAMPUS · PI AFASIZHEVA, INNA · 2015 to 2024
$4.6MSupplement: Advancing Proteomics Technologies to Decipher the Ubiquitin-Proteasome SystemR35GM145249 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI Lan Huang · 2022 to 2026
$3.2MWest/Midwest Consortium for High-Resolution Cryo Electron MicroscopyU24GM116792 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI AGBANDJE-MCKENNA, MAVIS, DOKLAND, TERJE · 2016 to 2020
$3.0MTRANSCRIPTIONAL CONTROL OF MITOCHONDRIAL GENE EXPRESSION IN TRYPANOSOMESR01AI152408 · NIAID · BOSTON UNIVERSITY MEDICAL CAMPUS · PI AFASIZHEV, RUSLAN · 2020 to 2024
$2.1MHIGH-END CRYOEM INSTRUMENT FOR UCLA ELECTRON IMAGING CTR FOR NANOMACHINES: AIDSS10RR023057 · NCRR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ZHOU, Z HONG · 2006 to 2006
$1.6MDirect Detection Device for atomic resolution cryoEM of macromolecular complexesS10OD018111 · OD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ZHOU, Z HONG · 2014 to 2014
$598kNCRR NIH HHS S10 RR023057NIAID NIH HHS R01 AI101057NIAID NIH HHS R01 AI113157NIAID NIH HHS R01 AI152408NIGMS NIH HHS R01 GM071940NIGMS NIH HHS R01 GM074830NIGMS NIH HHS R35 GM145249NIGMS NIH HHS U24 GM116792NIH HHS S10 OD018111
Abstract
In
Indexed as
RNA EditingRNA, Guide, KinetoplastidaRNA, MessengerRNA, ProtozoanRNA StabilityTrypanosoma brucei bruceiCryoelectron MicroscopyProtozoan ProteinsProtozoan ProteinsRNA, Guide, KinetoplastidaRNA, MessengerRNA, Protozoan
Identifiers
What Socratic holds
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Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.