Evidence map›Paper›PMID 37415598›Full record

ArticleFrontiers in genetics2023

Race/ethnicity-stratified fine-mapping of the MHC locus reveals genetic variants associated with late-onset asthma.

Eunice Y Lee, Wonson Choi, Adam B Burkholder, Lalith Perera, Jasmine A Mack, Frederick W Miller, Michael B Fessler, Donald N Cook, Peer W F Karmaus, Hideki Nakano and 8 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 5 citations in OpenAlex.

  1. Associations between genetic ancestry and allergic outcomes at 10 years among Black children.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Asthma Pathogenesis: Phenotypes, Therapies, and Gaps: Summary of the Aspen Lung Conference 2023.American journal of respiratory cell and molecular biology · 2024
    Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 3 institutions in 3 countries.

Eunice Y LeeBiostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, Durham, NC, United States.
Wonson ChoiGenomics and Bioinformatics Laboratory, Seoul National University, Seoul, Republic of Korea.
Adam B BurkholderNational Institute of Environmental Health Sciences, Durham, NC, United States.
Lalith PereraGenomic Integrity and Structural Biology Laboratory, National Institute of Environmental Health Sciences, Durham, NC, United States.
Jasmine A MackBiostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, Durham, NC, United States.
Frederick W MillerEnvironmental Autoimmunity Group, Clinical Research Branch, National Institute of Environmental Health Sciences, Durham, NC, United States.
Michael B FesslerImmunity, Inflammation and Disease Laboratory, National Institute of Environmental Health Sciences, Durham, NC, United States.
Donald N CookImmunity, Inflammation and Disease Laboratory, National Institute of Environmental Health Sciences, Durham, NC, United States.
Peer W F KarmausImmunity, Inflammation and Disease Laboratory, National Institute of Environmental Health Sciences, Durham, NC, United States.
Hideki NakanoImmunity, Inflammation and Disease Laboratory, National Institute of Environmental Health Sciences, Durham, NC, United States.
Stavros GarantziotisClinical Research Branch, National Institute of Environmental Health Sciences, Durham, NC, United States.
Jennifer H MadenspacherClinical Research Branch, National Institute of Environmental Health Sciences, Durham, NC, United States.
John S HouseBiostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, Durham, NC, United States.
Farida S AkhtariBiostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, Durham, NC, United States.
Charles S SchmittDivision of Translational Toxicology, National Institute of Environmental Health Sciences, Durham, NC, United States.
David C FargoNational Institute of Environmental Health Sciences, Durham, NC, United States.
Janet E HallClinical Research Branch, National Institute of Environmental Health Sciences, Durham, NC, United States.
Alison A Motsinger-ReifBiostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, Durham, NC, United States.
National Institute of Environmental Health Sciences · USSeoul National University · KRUniversity of Cambridge · GB

Funding

Molecular Genetics Support to Identify Gene/Environment Interactions in DiseaseZICES102546 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI GERRISH, KEVIN · 2009 to 2025
$30.5M
The Role of Hyaluronan And Inter-Alpha-Trypsin Inhibitor in Tissue InjuryZIAES102605 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI GARANTZIOTIS, STAVROS · 2009 to 2025
$22.6M
Macromolecular ModelingZICES043010 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI COPELAND, WILLIAM · 2012 to 2025
$5.7M
The Personalized Environment and Genes StudyZIAES103394 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI MOTSINGER-REIF, ALISON · 2023 to 2025
$2.7M
Development of Data Science MethodsZIAES103364 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI SCHMITT, CHARLES · 2021 to 2025
$1.6M
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ethnicityHLA alleleimmune functionlate-onset asthmaMHCrace

Identifiers

PMID37415598
PMCPMC10321602
OpenAlexW4381662426

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.