Evidence map›Paper›PMID 37417104›Full record

ReviewIndian journal of ophthalmology2023

Retinoblastoma: A review of the molecular basis of tumor development and its clinical correlation in shaping future targeted treatment strategies.

Shruti Rathore, Aman Verma, Ria Ratna, Navjot Marwa, Yagya Ghiya, Santosh G Honavar, Anil Tiwari, Sima Das, Akhil Varshney

Open access · diamondAbstract readReview
In one paragraph

Review in Indian journal of ophthalmology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Shruti RathoreOcular Oncology Services, Dr. Shroff's Charity Eye Hospital, New Delhi, India.
Aman VermaOcular Oncology Services, Dr. Shroff's Charity Eye Hospital, New Delhi, India.
Ria RatnaOcular Genetics Services, Dr. Shroff's Charity Eye Hospital, New Delhi, India.
Navjot MarwaOcular Oncology Services, Dr. Shroff's Charity Eye Hospital, New Delhi, India.
Yagya GhiyaOcular Oncology Services, Dr. Shroff's Charity Eye Hospital, New Delhi, India.
Santosh G HonavarOphthalmic Plastic Surgery, Orbit and Ocular Oncology, Centre for Sight, Hyderbad, Telangana, India.
Anil TiwariOcular Oncology Services, Dr. Shroff's Charity Eye Hospital, New Delhi, India.
Sima DasOcular Oncology Services, Dr. Shroff's Charity Eye Hospital, New Delhi, India.
Akhil VarshneyOcular Oncology Services, Dr. Shroff's Charity Eye Hospital, New Delhi, India.
Dr. Shroff’s Charity Eye Hospital · INCentre for Sight · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Retinoblastoma is a retinal cancer that affects children and is the most prevalent intraocular tumor worldwide. Despite tremendous breakthroughs in our understanding of the fundamental mechanisms that regulate progression of retinoblastoma, the development of targeted therapeutics for retinoblastoma has lagged. Our review highlights the current developments in the genetic, epigenetic, transcriptomic, and proteomic landscapes of retinoblastoma. We also discuss their clinical relevance and potential implications for future therapeutic development, with the aim to create a frontline multimodal therapy for retinoblastoma.

Indexed as

Retinal NeoplasmsRetinoblastomaChildCombined Modality TherapyHumansProteomicsBiomarkerepigeneticsgenomicsproteomicsretinoblastomatargeted therapeuticstherapeuticstranscriptomics

Identifiers

PMID37417104
PMCPMC10491038
OpenAlexW4383198676

What Socratic holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.