Evidence map›Paper›PMID 37425848›Full record

ArticlemedRxiv : the preprint server for health sciences2023

Discordance between gut-derived appetite hormones and energy intake in humans.

Aaron Hengist, Christina M Sciarrillo, Juen Guo, Mary Walter, Kevin D Hall

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Aaron HengistNational Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda MD, 20892, USA.
Christina M SciarrilloNational Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda MD, 20892, USA.
Juen GuoNational Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda MD, 20892, USA.
Mary WalterNational Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda MD, 20892, USA.
Kevin D HallNational Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda MD, 20892, USA.
National Institute of Diabetes and Digestive and Kidney Diseases · US

Funding

Modeling interactions of diet, exercise, metabolism, and weight change in humansZIADK013037 · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · 2025 to 2025
$680k
Intramural NIH HHS ZIA DK013037
6 · The paper itself

Abstract

Gut-derived hormones affect appetite and are thought to play an important role in body weight regulation. Dietary macronutrient composition can influence gut-derived appetite hormone concentrations, thereby providing theoretical basis for why some diets might facilitate weight loss better than others. We investigated postprandial gut-derived appetite hormones in 20 inpatient adults after 2 weeks of eating either a low carbohydrate (LC) or a low fat (LF) diet followed by the alternate diet in random order. A LC meal resulted in significantly greater postprandial GLP-1, GIP, and PYY but lower ghrelin compared to an isocaloric LF meal (all

Indexed as

AppetiteDietEnergy IntakeGut HormonesLow CarbohydrateLow FatPostprandial

Identifiers

PMID37425848
PMCPMC10327278
OpenAlexW4376129502

What Socratic holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.