Evidence map›Paper›PMID 37425907›Full record

ArticlebioRxiv : the preprint server for biology2023

Combinatorial selective ER-phagy remodels the ER during neurogenesis.

Melissa J Hoyer, Cristina Capitanio, Ian R Smith, Julia C Paoli, Anna Bieber, Yizhi Jiang, Joao A Paulo, Miguel A Gonzalez-Lozano, Wolfgang Baumeister, Florian Wilfling and 2 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Melissa J Hoyer
Cristina Capitanio
Ian R Smith
Julia C Paoli
Anna Bieber
Yizhi Jiang
Joao A Paulo
Miguel A Gonzalez-Lozano
Wolfgang Baumeister
Florian WilflingORCID 0000-0002-6559-7261
Brenda A Schulman
J Wade Harper
Harvard University · US

Funding

Endolysosomal Proteome Landscapes Through the Lens of Neurodegenerative Risk AllelesR01NS110395 · NINDS · HARVARD MEDICAL SCHOOL · PI JEFFREY W HARPER · 2018 to 2026
$4.1M
Regulation of PINK1 and PARKIN-Dependent MitophagyR01NS083524 · NINDS · HARVARD MEDICAL SCHOOL · PI HARPER, JEFFREY W · 2020 to 2024
$2.2M
Advancing Multiplexed Isobaric Tag-based Strategies for Proteome ProfilingR01GM132129 · NIGMS · HARVARD MEDICAL SCHOOL · PI PAULO, JOAO A · 2019 to 2023
$1.7M
NIGMS NIH HHS R01 GM132129NINDS NIH HHS R01 NS083524NINDS NIH HHS R01 NS110395
6 · The paper itself

Abstract

The endoplasmic reticulum (ER) employs a diverse proteome landscape to orchestrate many cellular functions ranging from protein and lipid synthesis to calcium ion flux and inter-organelle communication. A case in point concerns the process of neurogenesis: a refined tubular ER network is assembled via ER shaping proteins into the newly formed neuronal projections to create highly polarized dendrites and axons. Previous studies have suggested a role for autophagy in ER remodeling, as autophagy-deficient neurons

Identifiers

PMID37425907
PMCPMC10326971
OpenAlexW4382282519

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.