Evidence map›Paper›PMID 37428036›Full record

ArticleInfection and immunity2023

Legionella pneumophila Rhizoferrin Promotes Bacterial Biofilm Formation and Growth within Amoebae and Macrophages.

Alberto E Lopez, Lubov S Grigoryeva, Armando Barajas, Nicholas P Cianciotto

Open access · greenAbstract read
In one paragraph

Article in Infection and immunity, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Mucin stimulates the growth ofMicrobiology (Reading, England) · 2026
    Article
  4. Molecular evolution and adaptations ofFrontiers in cellular and infection microbiology · 2026
    Review
  5. Article
  6. Review
  7. Article
  8. mBio · 2025
    Article
  9. Review
  10. Ecology ofBiofilm · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Alberto E LopezDepartment of Microbiology and Immunology, Northwestern University Medical School, Chicago, Illinois, USA.
Lubov S GrigoryevaDepartment of Microbiology and Immunology, Northwestern University Medical School, Chicago, Illinois, USA.
Armando BarajasDepartment of Microbiology and Immunology, Northwestern University Medical School, Chicago, Illinois, USA.
Nicholas P CianciottoDepartment of Microbiology and Immunology, Northwestern University Medical School, Chicago, Illinois, USA.ORCID 0000-0002-9572-8322
Northwestern University · US

Funding

CELLULAR &MOLECULAR BASIS OF DISEASE TRAINING PROGRAMT32GM008061 · NIGMS · NORTHWESTERN UNIVERSITY · PI CARTHEW, RICHARD W. · 1985 to 2022
$17.1M
Mentoring For Success: Developing Fundamental Skills For Biomedical ResearchR25GM079300 · NIGMS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI MCGEE, RICHARD · 2007 to 2020
$6.6M
TRAINING PROGRAM IN IMMUNOLOGY &MOLECULAR PATHOGENESIST32AI007476 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Edward Benjamin Thorp · 1996 to 2026
$6.6M
Siderophores of Legionella pneumophilaR01AI139054 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI CIANCIOTTO, NICHOLAS P · 2018 to 2021
$1.8M
An IC-ICP-MS for advanced speciation and metalomics analysisS10OD020118 · OD · NORTHWESTERN UNIVERSITY · PI O'HALLORAN, THOMAS V · 2015 to 2015
$268k
NIAID NIH HHS R01 AI139054NIAID NIH HHS T32 AI007476NIGMS NIH HHS R25 GM079300NIGMS NIH HHS T32 GM008061NIH HHS S10 OD020118
6 · The paper itself

Abstract

Previously, we showed that Legionella pneumophila secretes rhizoferrin, a polycarboxylate siderophore that promotes bacterial growth in iron-deplete media and the murine lung. Yet, past studies failed to identify a role for the rhizoferrin biosynthetic gene (

Indexed as

AmoebaLegionella pneumophilaAnimalsBacterial ProteinsBiofilmsFerric CompoundsHumansIronMacrophagesMiceSiderophoresU937 CellsBacterial ProteinsFerric CompoundsIronrhizoferrinSiderophoresAcanthamoebabiofilmcytokinesFeoBLegionella pneumophilaLegionnaires' diseasemacrophagesrhizoferrinsiderophoreVermamoeba

Identifiers

PMID37428036
PMCPMC10429650
OpenAlexW4383709986

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.