Evidence map›Paper›PMID 37432153›Full record

ArticleNutrients2023

Impact of the FTO Gene Variation on Appetite and Fat Oxidation in Young Adults.

Jesús G Ponce-Gonzalez, Ángel Martínez-Ávila, Daniel Velázquez-Díaz, Alejandro Perez-Bey, Félix Gómez-Gallego, Alberto Marín-Galindo, Juan Corral-Pérez, Cristina Casals

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Jesús G Ponce-GonzalezExPhy Research Group, Department of Physical Education, Instituto de Investigación e Innovación Biomédica de Cádiz (INiBICA), Universidad de Cádiz, 11519 Cádiz, Spain.ORCID 0000-0002-5982-7761
Ángel Martínez-ÁvilaFaculty of Nursing Salus Infirmorum, University of Cádiz, 11001 Cádiz, Spain.ORCID 0000-0002-5297-649X
Daniel Velázquez-DíazExPhy Research Group, Department of Physical Education, Instituto de Investigación e Innovación Biomédica de Cádiz (INiBICA), Universidad de Cádiz, 11519 Cádiz, Spain.ORCID 0000-0001-6270-9208
Alejandro Perez-BeyGALENO Research Group, Department of Physical Education, Faculty of Education Sciences, University of Cádiz, Puerto Real, 11519 Cádiz, Spain.ORCID 0000-0002-9849-5544
Félix Gómez-GallegoFaculty of Health Sciences, University Rey Juan Carlos, 28922 Alcorcón, Spain.
Alberto Marín-GalindoExPhy Research Group, Department of Physical Education, Instituto de Investigación e Innovación Biomédica de Cádiz (INiBICA), Universidad de Cádiz, 11519 Cádiz, Spain.ORCID 0000-0002-0545-367X
Juan Corral-PérezExPhy Research Group, Department of Physical Education, Instituto de Investigación e Innovación Biomédica de Cádiz (INiBICA), Universidad de Cádiz, 11519 Cádiz, Spain.ORCID 0000-0002-6574-9827
Cristina CasalsExPhy Research Group, Department of Physical Education, Instituto de Investigación e Innovación Biomédica de Cádiz (INiBICA), Universidad de Cádiz, 11519 Cádiz, Spain.ORCID 0000-0002-6992-0492
Universidad de Cádiz · ESUniversidad Rey Juan Carlos · ES

Funding

Biomedical Research and Innovation Institute of Cadiz LI19/21IN-CO09Spanish Ministry of Science and Innovation PID2019-110063RA-I00Spanish Ministry of Science and Innovation PID2020-120034RA-I00University of Cádiz PR2016-051University of Cádiz PR2019-054
6 · The paper itself

Abstract

The FTO rs9939609 gene, which presents three polymorphisms (AA, AT, and TT), has been associated with the development of obesity through an increased fat accumulation; however, the associations of the gene with other physiological mechanisms, such as appetite or fat oxidation, are still unclear. Therefore, this study aims to evaluate the influence of the FTO rs9939609 gene on different obesity-related factors in young adults. The FTO rs9939609 polymorphism was genotyped in 73 participants (28 women, 22.27 ± 3.70 years). Obesity-related factors included dietary assessment, physical activity expenditure, body composition, appetite sensation, resting metabolic rate, maximal fat oxidation during exercise (MFO), and cardiorespiratory fitness. Our results showed that TT allele participants expressed higher values of hunger (

Indexed as

AppetiteHungerAllelesAlpha-Ketoglutarate-Dependent Dioxygenase FTOFemaleGenotypeHumansObesityYoung AdultAlpha-Ketoglutarate-Dependent Dioxygenase FTOFTO protein, humangenetic association studieslipid utilizationmetabolismphysical exercise

Identifiers

PMID37432153
PMCPMC10181223
OpenAlexW4366828541

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.