Evidence map›Paper›PMID 37438521›Full record

ArticleNature2023

Co-transplantation of autologous T

Tae-Yoon Park, Jeha Jeon, Nayeon Lee, Jisun Kim, Bin Song, Jung-Ho Kim, Sang-Kyou Lee, Dongxin Liu, Young Cha, Minseon Kim and 5 more

Open access · greenAbstract read
In one paragraph

Article in Nature, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed, 1 pooled it
17.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

70 citing papers in PubMed, 1 synthesis or guideline pooled it, 111 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Selective CaStem cell reports · 2026
    Article
  11. Review
  12. Review
  13. Review
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article

10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 2 countries.

Tae-Yoon Park *Molecular Neurobiology Laboratory, Department of Psychiatry and McLean Hospital, Harvard Medical School, Belmont, MA, USA.ORCID 0000-0001-6358-9375
Jeha Jeon *Molecular Neurobiology Laboratory, Department of Psychiatry and McLean Hospital, Harvard Medical School, Belmont, MA, USA.ORCID 0000-0003-3779-2446
Nayeon LeeMolecular Neurobiology Laboratory, Department of Psychiatry and McLean Hospital, Harvard Medical School, Belmont, MA, USA.ORCID 0000-0002-3377-2301
Jisun KimMolecular Neurobiology Laboratory, Department of Psychiatry and McLean Hospital, Harvard Medical School, Belmont, MA, USA.
Bin SongMolecular Neurobiology Laboratory, Department of Psychiatry and McLean Hospital, Harvard Medical School, Belmont, MA, USA.
Jung-Ho KimDepartment of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul, Republic of Korea.
Sang-Kyou LeeDepartment of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul, Republic of Korea.
Dongxin LiuMolecular Neurobiology Laboratory, Department of Psychiatry and McLean Hospital, Harvard Medical School, Belmont, MA, USA.ORCID 0000-0002-0956-5142
Young ChaMolecular Neurobiology Laboratory, Department of Psychiatry and McLean Hospital, Harvard Medical School, Belmont, MA, USA.ORCID 0000-0001-7647-0699
Minseon KimMolecular Neurobiology Laboratory, Department of Psychiatry and McLean Hospital, Harvard Medical School, Belmont, MA, USA.ORCID 0000-0002-1193-7937
Pierre LeblancMolecular Neurobiology Laboratory, Department of Psychiatry and McLean Hospital, Harvard Medical School, Belmont, MA, USA.ORCID 0000-0001-8756-2396
Todd M HerringtonDepartment of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Bob S CarterDepartment of Neurosurgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Jeffrey S SchweitzerDepartment of Neurosurgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.ORCID 0000-0003-4079-0791
Kwang-Soo KimMolecular Neurobiology Laboratory, Department of Psychiatry and McLean Hospital, Harvard Medical School, Belmont, MA, USA. kskim@mclean.harvard.edu.ORCID 0000-0002-6081-9857
Harvard University · USYonsei University · KR

Funding

Protein-induced human iPS cells for personalized cell therapy of PDR01NS070577 · NINDS · MCLEAN HOSPITAL · PI KIM, KWANG-SOO, KORDOWER, JEFFREY H · 2010 to 2020
$4.9M
Biorepository of iPSC lines from diverse rat strains for regenerative medicine researchR24OD024622 · OD · MCLEAN HOSPITAL · PI KIM, KWANG-SOO, KONG, SEK WON · 2018 to 2021
$3.4M
Human iPSC-Based Personalized Cell Therapy of PDR01NS129188 · NINDS · MCLEAN HOSPITAL · PI Kwang-Soo Kim, Sek Won Kong · 2023 to 2026
$2.8M
Crosstalk Between Nurr1 and Risk Factors of Parkinson's Disease and its Regulation by Nurr1's LigandsR01NS127391 · NINDS · MCLEAN HOSPITAL · PI Kwang-Soo Kim · 2023 to 2026
$1.8M
Using phasic stimulation to explore the subthalamic nucleus - cortical decision-making network in Parkinson's diseaseK23NS099380 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI HERRINGTON, TODD · 2017 to 2021
$1.0M
NIH HHS R24 OD024622NINDS NIH HHS K23 NS099380NINDS NIH HHS R01 NS070577NINDS NIH HHS R01 NS127391NINDS NIH HHS R01 NS129188
6 · The paper itself

Abstract

The specific loss of midbrain dopamine neurons (mDANs) causes major motor dysfunction in Parkinson's disease, which makes cell replacement a promising therapeutic approach

Indexed as

Cell- and Tissue-Based TherapyDopaminergic NeuronsGraft SurvivalNeuroinflammatory DiseasesParkinson DiseaseT-Lymphocytes, RegulatoryTyrosine 3-MonooxygenaseAnimalsCell DeathCell ProliferationDopamineHumansInduced Pluripotent Stem CellsMesencephalonMiceNeostriatumDopamineOxidopamineTyrosine 3-Monooxygenase

Identifiers

PMID37438521
PMCPMC12012854
OpenAlexW4384008968

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.