Evidence map›Paper›PMID 37439240›Full record

ArticleJournal of applied physiology (Bethesda, Md. : 1985)2023

Role of lung lobar sliding on parenchymal distortion during breathing.

Adam E Galloy, Joseph M Reinhardt, Madhavan L Raghavan

Open access · greenAbstract read
In one paragraph

Article in Journal of applied physiology (Bethesda, Md. : 1985), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Adam E GalloyRoy J. Carver Department of Biomedical Engineering, University of Iowa, Iowa City, Iowa, United States.
Joseph M ReinhardtRoy J. Carver Department of Biomedical Engineering, University of Iowa, Iowa City, Iowa, United States.
Madhavan L RaghavanRoy J. Carver Department of Biomedical Engineering, University of Iowa, Iowa City, Iowa, United States.ORCID 0000-0002-0978-7829
University of Iowa · US

Funding

Vector Core-Core 2P30DK054759 · NIDDK · UNIVERSITY OF IOWA · PI Alejandro Antonio Pezzulo · 1998 to 2026
$30.5M
Lung Biomechanics and Disease Progression in SPIROMICSR01HL142625 · NHLBI · UNIVERSITY OF IOWA · PI REINHARDT, JOSEPH M · 2018 to 2021
$2.2M
Iowa Lung Imaging Training ProgramT32HL144461 · NHLBI · UNIVERSITY OF IOWA · PI HOFFMAN, ERIC ALFRED, REINHARDT, JOSEPH M · 2019 to 2023
$1.6M
NHLBI NIH HHS R01 HL142625NHLBI NIH HHS T32 HL144461NIDDK NIH HHS P30 DK054759
6 · The paper itself

Abstract

Sliding between lung lobes along lobar fissures is a poorly understood aspect of lung mechanics. The objective of this study was to test the hypothesis that lobar sliding helps reduce distortion in the lung parenchyma during breathing. Finite element models of left lungs with geometries and boundary conditions derived from medical images of human subjects were developed. Effect of lobar sliding was studied by comparing nonlinear finite elastic contact mechanics simulations that allowed and disallowed lobar sliding. Lung parenchymal distortion during simulated breath-holds and tidal breathing was quantified with the model's spatial mean anisotropic deformation index (ADI), a measure of directional preference in volume change that varies spatially in the lung. Models that allowed lobar sliding had significantly lower mean ADI (i.e., lesser parenchymal distortion) than models that disallowed lobar sliding under simulations of both tidal breathing (5.3% median difference,

Indexed as

LungRespirationFunctional Residual CapacityHumansRespiratory Function TestsTotal Lung Capacityfinite element methodlobar fissureslobar slidinglung mechanicstissue mechanics

Identifiers

PMID37439240
PMCPMC10538991
OpenAlexW4384120608

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.