Evidence map›Paper›PMID 37445362›Full record

ArticleJournal of clinical medicine2023

Subcutaneous Immunotherapy (SCIT) with the New Polymerized Molecular Allergoid Alt a1: A Pilot Study in Children with Allergic Rhinitis Sensitized to Alternaria Alternata.

Giulia Brindisi, Alessandra Gori, Caterina Anania, Ivana Martinelli, Martina Capponi, Giovanna De Castro, Anna Maria Zicari

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Medicina (Kaunas, Lithuania) · 2025
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Giulia BrindisiDepartment of Mother-Child, Urological Science, Sapienza University of Rome, 00161 Rome, Italy.ORCID 0000-0001-5059-6082
Alessandra GoriDepartment of Mother-Child, Urological Science, Sapienza University of Rome, 00161 Rome, Italy.
Caterina AnaniaDepartment of Mother-Child, Urological Science, Sapienza University of Rome, 00161 Rome, Italy.
Ivana MartinelliDepartment of Mother-Child, Urological Science, Sapienza University of Rome, 00161 Rome, Italy.
Martina CapponiDepartment of Mother-Child, Urological Science, Sapienza University of Rome, 00161 Rome, Italy.
Giovanna De CastroDepartment of Mother-Child, Urological Science, Sapienza University of Rome, 00161 Rome, Italy.
Anna Maria ZicariDepartment of Mother-Child, Urological Science, Sapienza University of Rome, 00161 Rome, Italy.
Sapienza University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe followed the effects of a new SCIT with a chemically polymerized allergen Alt a1, evaluating the trend of clinical and functional parameters in an observational-prospective study.

methods42 children with AR and intermittent asthma sensitized to A.A.: 17 patients started SCIT (Modigoid

resultsPatients treated with Modigoid presented a statistically significant (

conclusionsThe new SCIT for Alt a1 significantly improves AR symptoms from a subjective, objective point of view and laboratory and functional parameters.

Indexed as

allergic rhinitis (AR)Alt a1Alternaria Alternataanterior active rhinomanometry (AAR)childrenModigoidnasal citologynasal FeNO (nFeNO)precision medicinesubcutaneus immunotherapy

Identifiers

PMID37445362
PMCPMC10342936
OpenAlexW4382401731

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.