Evidence map›Paper›PMID 37445600›Full record

ReviewInternational journal of molecular sciences2023

The Diagnostic Potential of the Human Blood Microbiome: Are We Dreaming or Awake?

Francesca Sciarra, Edoardo Franceschini, Federica Campolo, Mary Anna Venneri

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Blood microbiome signatures in the REM sleep behavior disorder-Lewy body disease continuum.Journal of neural transmission (Vienna, Austria : 1996) · 2025
    Article
  9. Pathological Alterations in Human Blood Microbiome-An Updated Review.International journal of molecular sciences · 2025
    Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. [Erythrocyte morphological alterations as predictors of kidney injury severity].Revista medica del Instituto Mexicano del Seguro Social · 2024
    Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Francesca SciarraDepartment of Experimental Medicine, Sapienza University of Rome, 00185 Rome, Italy.
Edoardo FranceschiniDepartment of Experimental Medicine, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0009-0008-3769-6706
Federica CampoloDepartment of Experimental Medicine, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0002-9290-874X
Mary Anna VenneriDepartment of Experimental Medicine, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0002-0687-8135
Sapienza University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human blood has historically been considered a sterile environment. Recently, a thriving microbiome dominated by Firmicutes, Actinobacteria, Proteobacteria, and Bacteroidetes phyla was detected in healthy blood. The localization of these microbes is restricted to some blood cell populations, particularly the peripheral blood mononuclear cells and erythrocytes. It was hypothesized that the blood microbiome originates from the skin-oral-gut axis. In addition, many studies have evaluated the potential of blood microbiome dysbiosis as a prognostic marker in cardiovascular diseases, cirrhosis, severe liver fibrosis, severe acute pancreatitis, type 2 diabetes, and chronic kidney diseases. The present review aims to summarize current findings and most recent evidence in the field.

Indexed as

Diabetes Mellitus, Type 2MicrobiotaPancreatitisAcute DiseaseDysbiosisHumansLeukocytes, MononuclearLiver CirrhosisWakefulnessbacteriadysbiosishuman blood microbiomemicrobiomeprognostic marker

Identifiers

PMID37445600
PMCPMC10341833
OpenAlexW4381665320

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.