Evidence mapPaperPMID 37445802Full record

ReviewInternational journal of molecular sciences2023

Exosome-Autophagy Crosstalk in Enveloped Virus Infection.

Yuqi Wang, Linzhu Ren, Haocheng Bai, Qing Jin, Liying Zhang

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. Research progress on the mechanism of exosome-mediated virus infection.Frontiers in cellular and infection microbiology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Yuqi WangKey Lab for Zoonoses Research, College of Animal Sciences, Ministry of Education, Jilin University, Changchun 130062, China.
Linzhu RenKey Lab for Zoonoses Research, College of Animal Sciences, Ministry of Education, Jilin University, Changchun 130062, China.ORCID 0000-0002-1092-6435
Haocheng BaiKey Lab for Zoonoses Research, College of Animal Sciences, Ministry of Education, Jilin University, Changchun 130062, China.
Qing JinKey Lab for Zoonoses Research, College of Animal Sciences, Ministry of Education, Jilin University, Changchun 130062, China.
Liying ZhangKey Lab for Zoonoses Research, College of Animal Sciences, Ministry of Education, Jilin University, Changchun 130062, China.
Jilin University · CN

Funding

Jilin Province Science and Technology Development Projects Grant No. 20200402043NCNational Natural Science Foundation of China No. 31972710
6 · The paper itself

Abstract

Exosomes, which are extracellular vesicles (EVs) predominantly present in bodily fluids, participate in various physiological processes. Autophagy, an intracellular degradation mechanism, eliminates proteins and damaged organelles by forming double-membrane autophagosomes. These autophagosomes subsequently merge with lysosomes for target degradation. The interaction between autophagy and endosomal/exosomal pathways can occur at different stages, exerting significant influences on normal physiology and human diseases. The interplay between exosomes and the autophagy pathway is intricate. Exosomes exhibit a cytoprotective role by inducing intracellular autophagy, while autophagy modulates the biogenesis and degradation of exosomes. Research indicates that exosomes and autophagy contribute to the infection process of numerous enveloped viruses. Enveloped viruses, comprising viral nucleic acid, proteins, or virions, can be encapsulated within exosomes and transferred between cells via exosomal transport. Consequently, exosomes play a crucial role in the infection of certain viral diseases. This review presents recent findings on the interplay between exosomes and autophagy, as well as their implications in the infection of enveloped viruses, thereby offering valuable insights into the pathogenesis and vaccine research of enveloped virus infection.

Indexed as

ExosomesExtracellular VesiclesAutophagosomesAutophagyEndosomesHumansautophagyextracellular vesiclesrelationshipviruses

Identifiers

PMID37445802
PMCPMC10341880
OpenAlexW4382195513

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.