Evidence map›Paper›PMID 37445823›Full record

ArticleInternational journal of molecular sciences2023

The Sizes and Composition of HDL-Cholesterol Are Significantly Associated with Inflammation in Rheumatoid Arthritis Patients.

Ching-Kun Chang, En-Pei Isabel Chiang, Kuang-Hsi Chang, Kuo-Tung Tang, Po-Ku Chen, Hei-Tung Yip, Chu-Huang Chen, Der-Yuan Chen

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

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  10. Dysfunctional high-density lipoprotein: an updated review.Frontiers in cardiovascular medicine · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Ching-Kun ChangRheumatology and Immunology Center, China Medical University Hospital, Taichung 404, Taiwan.ORCID 0000-0001-7818-0847
En-Pei Isabel ChiangDepartment of Food Science and Biotechnology, National Chung Hsing University, Taichung 402, Taiwan.ORCID 0000-0002-0158-0962
Kuang-Hsi ChangDepartment of Medical Research, Tungs' Taichung Metroharbor Hospital, Taichung 435, Taiwan.ORCID 0000-0002-4453-0068
Kuo-Tung TangDivision of Allergy, Immunology and Rheumatology, Taichung Veterans General Hospital, Taichung 407, Taiwan.
Po-Ku ChenRheumatology and Immunology Center, China Medical University Hospital, Taichung 404, Taiwan.
Hei-Tung YipCollege of Medicine, China Medical University, Taichung 404, Taiwan.ORCID 0000-0003-4077-3473
Chu-Huang ChenVascular and Medicinal Research, Texas Heart Institute, Houston, TX 77030, USA.
Der-Yuan ChenRheumatology and Immunology Center, China Medical University Hospital, Taichung 404, Taiwan.ORCID 0000-0003-1266-1423
China Medical University · TWNational Chung Hsing University · TWNational Yang Ming Chiao Tung University · TWShinshu University · JP

Funding

China Medical University Hospital Taiwan DMR-112-185Ministry of Science and Technology Taiwan MOST 111-2314-B-039-011
6 · The paper itself

Abstract

Rheumatoid arthritis (RA), a chronic inflammatory disease, carries a significant burden of atherosclerotic cardiovascular diseases (ASCVD). With their heterogeneous composition, high-density lipoprotein (HDL) particles have varied athero-protective properties, and some may even increase ASCVD risk. In this prospective and cross-sectional study, we aimed to examine the relationship between HDL sizes/metabolites and inflammation in RA. Using

Indexed as

Arthritis, RheumatoidInflammationCholesterolCholesterol, HDLCross-Sectional StudiesHumansLipoproteins, HDLProspective StudiesCholesterolCholesterol, HDLLipoproteins, HDLanti-citrullinated peptide antibodies (ACPA)high-density lipoprotein (HDL)inflammationlipid metabolitesrheumatoid arthritis (RA)

Identifiers

PMID37445823
PMCPMC10341560
OpenAlexW4382460471

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.