Evidence map›Paper›PMID 37446157›Full record

ReviewInternational journal of molecular sciences2023

Immunomodulation Therapies for Atherosclerosis: The Past, the Present, and the Future.

Dalgisio Lecis, Gianluca Massaro, Daniela Benedetto, Marco Di Luozzo, Giulio Russo, Alessandro Mauriello, Massimo Federici, Giuseppe Massimo Sangiorgi

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Dalgisio LecisDivision of Cardiology, "Tor Vergata" University Hospital, Viale Oxford 81, 00133 Rome, Italy.
Gianluca MassaroDivision of Cardiology, "Tor Vergata" University Hospital, Viale Oxford 81, 00133 Rome, Italy.ORCID 0000-0003-3007-5313
Daniela BenedettoDivision of Cardiology, "Tor Vergata" University Hospital, Viale Oxford 81, 00133 Rome, Italy.
Marco Di LuozzoDivision of Cardiology, "Tor Vergata" University Hospital, Viale Oxford 81, 00133 Rome, Italy.
Giulio RussoDivision of Cardiology, "Tor Vergata" University Hospital, Viale Oxford 81, 00133 Rome, Italy.
Alessandro MaurielloDepartment of Experimental Medicine, University "Tor Vergata", 00133 Rome, Italy.ORCID 0000-0002-7351-5676
Massimo FedericiDepartment of Systemic Medicine, University "Tor Vergata", 00133 Rome, Italy.
Giuseppe Massimo SangiorgiDivision of Cardiology, "Tor Vergata" University Hospital, Viale Oxford 81, 00133 Rome, Italy.ORCID 0000-0001-5862-1967
University of Rome Tor Vergata · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atherosclerotic cardiovascular disease is the most common cause of morbidity and death worldwide. Recent studies have demonstrated that this chronic inflammatory disease of the arterial wall can be controlled through the modulation of immune system activity. Many patients with cardiovascular disease remain at elevated risk of recurrent events despite receiving current, state-of-the-art preventive medical treatment. Much of this residual risk is attributed to inflammation. Therefore, finding new treatment strategies for this category of patients became of common interest. This review will discuss the experimental and clinical data supporting the possibility of developing immune-based therapies for lowering cardiovascular risk, explicitly focusing on vaccination strategies.

Indexed as

AtherosclerosisImmunomodulationAdaptive ImmunityAutoantigensClinical Trials as TopicHeart Disease Risk FactorsHumansImmunity, HumoralImmunity, InnateInflammationVaccinationVaccinesAutoantigensVaccinesatherosclerosiscardiovascular diseaseimmune-modulation therapiesinflammationvaccine

Identifiers

PMID37446157
PMCPMC10342012
OpenAlexW4382982800

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.