Evidence map›Paper›PMID 37446344›Full record

ArticleInternational journal of molecular sciences2023

Lamin A/C Ablation Restricted to Vascular Smooth Muscle Cells, Cardiomyocytes, and Cardiac Fibroblasts Causes Cardiac and Vascular Dysfunction.

Alberto Del Monte-Monge, Íñigo Ruiz-Polo de Lara, Pilar Gonzalo, Carla Espinós-Estévez, María González-Amor, Miguel de la Fuente-Pérez, María J Andrés-Manzano, Víctor Fanjul, Juan R Gimeno, Roberto Barriales-Villa and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. G protein regulation by RGS proteins in the pathophysiology of dilated cardiomyopathy.American journal of physiology. Heart and circulatory physiology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Alberto Del Monte-MongeCentro Nacional de Investigaciones Cardiovasculares (CNIC), Melchor Fernández Almagro 3, 28029 Madrid, Spain.
Íñigo Ruiz-Polo de LaraCentro Nacional de Investigaciones Cardiovasculares (CNIC), Melchor Fernández Almagro 3, 28029 Madrid, Spain.ORCID 0000-0001-8345-1525
Pilar GonzaloCentro Nacional de Investigaciones Cardiovasculares (CNIC), Melchor Fernández Almagro 3, 28029 Madrid, Spain.
Carla Espinós-EstévezCentro Nacional de Investigaciones Cardiovasculares (CNIC), Melchor Fernández Almagro 3, 28029 Madrid, Spain.ORCID 0000-0001-5759-0513
María González-AmorCentro Nacional de Investigaciones Cardiovasculares (CNIC), Melchor Fernández Almagro 3, 28029 Madrid, Spain.ORCID 0000-0002-5919-6760
Miguel de la Fuente-PérezCentro Nacional de Investigaciones Cardiovasculares (CNIC), Melchor Fernández Almagro 3, 28029 Madrid, Spain.
María J Andrés-ManzanoCentro Nacional de Investigaciones Cardiovasculares (CNIC), Melchor Fernández Almagro 3, 28029 Madrid, Spain.
Víctor FanjulCentro Nacional de Investigaciones Cardiovasculares (CNIC), Melchor Fernández Almagro 3, 28029 Madrid, Spain.
Juan R GimenoCentro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBERCV), 28029 Madrid, Spain.
Roberto Barriales-VillaCentro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBERCV), 28029 Madrid, Spain.
Beatriz DoradoCentro Nacional de Investigaciones Cardiovasculares (CNIC), Melchor Fernández Almagro 3, 28029 Madrid, Spain.ORCID 0000-0002-1958-4558
Vicente AndrésCentro Nacional de Investigaciones Cardiovasculares (CNIC), Melchor Fernández Almagro 3, 28029 Madrid, Spain.ORCID 0000-0002-0125-7209
Spanish National Centre for Cardiovascular Research · ESCentro de Investigación en Red en Enfermedades Cardiovasculares · ES

Funding

Fundación laCaixa LCF/BQ/DR19/1170012 and LCF/BQ/DE14/10320024Ministerio de Ciencia e Innovación BES-2014-067791Ministerio de Ciencia e Innovación CEX2020-001041-SMinisterio de Ciencia e Innovación SAF2016-79490-R and PID2019-108489RB-I00Ministerio de Cierncia e Innovación PRE2020-092264 and FJC 2021-047576-I
6 · The paper itself

Abstract

Mutations in the

Indexed as

Cardiomyopathy, DilatedMyocytes, CardiacAnimalsHumansLamin Type AMiceMuscle, Smooth, VascularMutationStroke VolumeVentricular Function, LeftLamin Type Adilated cardiomyopathylamin A/Claminopathiestransgenic micevascular dysfunctionvascular smooth muscle cell

Identifiers

PMID37446344
PMCPMC10342548
OpenAlexW4383536450

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.