Evidence map›Paper›PMID 37446702›Full record

ArticleMolecules (Basel, Switzerland)2023

Investigation of New Psychoactive Substances (NPS), Other Illicit Drugs, and Drug-Related Compounds in a Taiwanese Wastewater Sample Using High-Resolution Mass-Spectrometry-Based Targeted and Suspect Screening.

Yuan-Chih Chen, Jen-Yi Hsu, Chih-Wei Chang, Pin-Yu Chen, Yung-Chieh Lin, I-Lin Hsu, Chiau-Jun Chu, Yen-Ping Lin, Pao-Chi Liao

Abstract read
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In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yuan-Chih ChenDepartment of Environmental and Occupational Health, College of Medicine, National Cheng Kung University, Tainan 704, Taiwan.
Jen-Yi HsuDepartment of Environmental and Occupational Health, College of Medicine, National Cheng Kung University, Tainan 704, Taiwan.
Chih-Wei ChangDepartment of Environmental and Occupational Health, College of Medicine, National Cheng Kung University, Tainan 704, Taiwan.
Pin-Yu ChenDepartment of Environmental and Occupational Health, College of Medicine, National Cheng Kung University, Tainan 704, Taiwan.
Yung-Chieh LinDepartment of Environmental and Occupational Health, College of Medicine, National Cheng Kung University, Tainan 704, Taiwan.
I-Lin HsuPublic Health Bureau, Tainan City Government, Tainan 704, Taiwan.
Chiau-Jun ChuPublic Health Bureau, Tainan City Government, Tainan 704, Taiwan.
Yen-Ping LinPublic Health Bureau, Tainan City Government, Tainan 704, Taiwan.
Pao-Chi LiaoDepartment of Environmental and Occupational Health, College of Medicine, National Cheng Kung University, Tainan 704, Taiwan.ORCID 0000-0001-8510-9870

Funding

Taiwan Food and Drug Administration MOHW112-FDA-D-114-000632
6 · The paper itself

Abstract

The proliferation of new psychoactive substances (NPSs) in recent years has posed a significant challenge to public health. Traditional monitoring methods have proven insufficient in tracking these constantly evolving substances, leading to the development of alternative approaches such as wastewater-based epidemiology (WBE). The present study aims to utilize high-resolution mass spectrometry (HRMS)-based targeted and suspect screening to profile NPS, other illicit drugs, and drug-related compounds in a Taiwanese wastewater sample. For the targeted analysis, 8 out 18 standards of illicit drugs have been identified. The suspect screening approach based on approximately 3600 substances in the SWGDRUG library can further identify 92 compounds, including opiate analgesics, synthetic cathinones, phenylalkylamines derivatives, phenethylamine derivatives, tryptamine derivatives, steroids, and ephedrine-related compounds. Additionally, the presence of 5-methoxy-2-aminoindane (MEAI) in the wastewater indicates that drug dealers have recently sold this potential NPS to evade drug regulations. This study firstly reports the HRMS-based comprehensive profile of NPS, other illicit drugs, and drug-related compounds in Taiwan, which could be applied as biomarkers for estimating the consumption of drugs.

Indexed as

Illicit DrugsWastewaterBiomarkersMass SpectrometryPsychotropic DrugsBiomarkersIllicit DrugsPsychotropic DrugsWastewaterhigh-resolution mass spectrometrynew psychoactive substancessuspect screeningTaiwanwastewater-based epidemiology

Identifiers

PMID37446702
PMCPMC10343774

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.