Evidence mapPaperPMID 37447295Full record

ArticleNutrients2023

Maternal Pre-Pregnancy BMI, Offspring Adiposity in Late Childhood, and Age of Weaning: A Causal Mediation Analysis.

Jie Zhang, Gemma L Clayton, Stefan Nygaard Hansen, Anja Olsen, Deborah A Lawlor, Christina C Dahm

Abstract read
In one paragraph

Article in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jie ZhangDepartment of Public Health, Aarhus University, DK-8000 Aarhus, Denmark.ORCID 0000-0002-1985-5485
Gemma L ClaytonPopulation Health Sciences, Bristol Medical School, University of Bristol, Bristol BS8 2BN, UK.
Stefan Nygaard HansenDepartment of Public Health, Aarhus University, DK-8000 Aarhus, Denmark.
Anja OlsenDepartment of Public Health, Aarhus University, DK-8000 Aarhus, Denmark.ORCID 0000-0003-4788-503X
Deborah A LawlorPopulation Health Sciences, Bristol Medical School, University of Bristol, Bristol BS8 2BN, UK.
Christina C DahmDepartment of Public Health, Aarhus University, DK-8000 Aarhus, Denmark.ORCID 0000-0003-0481-2893

Funding

Graduate School of Health and the Aarhus University Research Foundation AUFF-F-2016-FLS-8-15John Templeton Foundation Grant ID: 60828the British Heart Foundation AA/18/1/34219 and CS/16/4/32482the European Union's Horizon 2020 research and innovation programme 733206the University of Bristol and the UK Medical Research Council MC_UU_00011/6UK Medical Research Council and Wellcome 217065/Z/19/ZWellcome TrustWellcome Trust and MRC (core) 076467/Z/05/Z, 102215/2/13/2
6 · The paper itself

Abstract

Infant feeding practices have been hypothesized to influence offspring's body mass index (BMI) later in life, and women with overweight or obesity tend to wean their infants earlier than women with healthy BMI. We, therefore, aimed to investigate how much early age of weaning mediated the maternal-offspring adiposity relationship. The study included 4920 mother-child pairs from the Avon Longitudinal Study of Parents and Children birth cohort. G-computation was applied to estimate the natural direct (NDE) and indirect (NIE) effects, via the age of weaning (<3 months, 3 months, >3 months), of maternal pre-pregnancy overweight or obesity on offspring's BMI and fat mass index. The NDE of maternal overweight or obesity on offspring BMI at 17 years old was 2.63 kg/m

Indexed as

AdiposityOverweightAdolescentBody Mass IndexChildFemaleHumansInfantLongitudinal StudiesMediation AnalysisObesityPregnancyWeaningage of weaningALSPACbody mass indexmediation

Identifiers

PMID37447295
PMCPMC10343873

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.