Evidence map›Paper›PMID 37448529›Full record

ReviewMayo Clinic proceedings. Innovations, quality & outcomes2023

Contemporary Monoclonal Antibody Utilization in Glomerular Diseases.

Iyad Mansour, Sangeetha Murugapandian, Bekir Tanriover, Bijin Thajudeen

Abstract readReview
In one paragraph

Review in Mayo Clinic proceedings. Innovations, quality & outcomes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Iyad MansourDivision of Nephrology, College of Medicine, The University of Arizona, Tucson.
Sangeetha MurugapandianDivision of Nephrology, College of Medicine, The University of Arizona, Tucson.
Bekir TanrioverDivision of Nephrology, College of Medicine, The University of Arizona, Tucson.
Bijin ThajudeenDivision of Nephrology, College of Medicine, The University of Arizona, Tucson.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Therapeutic monoclonal antibodies (MAbs) have been one of the fastest growing drug classes in the past 2 decades and are indicated in the treatment of cancer, autoimmune disorders, solid organ transplantation, and glomerular diseases. The Food and Drug Administration has approved 100 MAbs between 1986 and 2021, and MAbs account for 20% of Food and Drug Administration's new drug approval every year. MAbs are preferred over traditional immunosuppressive agents because of their high specificity, reduced number of drug-drug interactions, and low toxicity, which make them a prime example of personalized medicine. In this review article, we provide an overview of the taxonomy, pharmacology, and therapeutic applications of MAbs in glomerular diseases. We searched the literature through PubMed using the following search terms:

Identifiers

PMID37448529
PMCPMC10338194

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.