Evidence map›Paper›PMID 37448685›Full record

ArticleIranian journal of microbiology2023

Determine phenotypical patterns of resistance to antibiotics in COVID-19 patients with associated bacterial infection: largest medical center in Iran.

Esmaeil Mohammadnejad, Arash Seifi, Reza Ghanei Gheshlagh, Amir Aliramezani, Samrand Fattah Ghazi, Mohammadreza Salehi, Seyed Ali Dehghan Manshadi, Amirhossein Orandi

Open access · diamondAbstract read
In one paragraph

Article in Iranian journal of microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Genomic features and fitness cost of co-existence ofFrontiers in cellular and infection microbiology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Esmaeil MohammadnejadResearch Center for Antibiotic Stewardship and Antimicrobial Resistance, Department of Medical-Surgical Nursing and Basic Sciences, School of Nursing and Midwifery, Tehran University of Medical Sciences, Tehran, Iran.
Arash SeifiResearch Center for Antibiotic Stewardship and Antimicrobial Resistance, Department of Infectious Disease, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Reza Ghanei GheshlaghSocial Determinants of Health Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Iran.
Amir AliramezaniDepartment of Microbiology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland.
Samrand Fattah GhaziDepartment of Anesthesiology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Mohammadreza SalehiResearch Center for Antibiotic Stewardship and Antimicrobial Resistance, Department of Infectious Disease, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Seyed Ali Dehghan ManshadiDepartment of Infectious Disease and Tropical Medicine, School of Medicine, Iranian Research Center for HIV/AID, Iranian Institute for reduction of High-Risk Behaviors, Tehran University of Medical Sciences, Tehran, Iran.
Amirhossein OrandiDepartment of Anesthesiology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Tehran University of Medical Sciences · IRIranian Institute for Health Sciences Research · IRJagiellonian University · PLKurdistan University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Objectives: Antibacterial resistance (AMR) is a serious threat and major concern, especially in developing countries. Therefore, we aimed to determine phenotypical patterns of resistance to antibiotics in COVID-19 patients with associated bacterial infection in intensive care units. Materials and Methods: In this cross-sectional study, 6524 COVID-19 patients admitted for more than 48 h in the ICUs of Imam Khomeini Complex Hospital (IKCH) in Tehran from March 2020 to January 2022 were included in the study with initial diagnosis of COVID-19 (PCR test and chest imaging). Data were collected regarding severity of the illness, primary reason for ICU admission, presence of risk factors, presence of infection, length of ICU and hospital stay, microbial type, and antibiotic resistance. In this study, the pattern of antibiotic resistance was determined using the Kirby-Bauer disk diffusion method. Results: In this study, 439 (37.5%) were ventilator-related events (VAEs), and 46% of all hospitalized patients had an underlying disease. The most common microorganisms in COVID-19 patients were carbapenem resistant Conclusion: A study on AMR surveillance is the need of the hour as it will help centers to generate local antibiograms that will further help formulate national data. It will guide doctors to choose the appropriate empiric treatment, and these studies will be the basis for establishing antimicrobial surveillance and monitoring and regulating of the use of antimicrobials.

Indexed as

Antimicrobial resistanceCOVID-19Intensive care unitPneumoniaSurveillance

Identifiers

PMID37448685
PMCPMC10336291
OpenAlexW4381113359

What Socratic holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.