Evidence map›Paper›PMID 37450065›Full record

ReviewJournal of mammary gland biology and neoplasia2023

Imagine beyond: recent breakthroughs and next challenges in mammary gland biology and breast cancer research.

Renée van Amerongen, Mohamed Bentires-Alj, Antonius L van Boxtel, Robert B Clarke, Silvia Fre, Eva Gonzalez Suarez, Richard Iggo, Martin Jechlinger, Jos Jonkers, Marja L Mikkola and 3 more

Abstract readReview
In one paragraph

Review in Journal of mammary gland biology and neoplasia, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. A Guide to Breast Cancer Research: An Introduction.Advances in experimental medicine and biology · 2025
    Article
  4. A molecular toolbox to study progesterone receptor signaling.Journal of mammary gland biology and neoplasia · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Renée van AmerongenDevelopmental, Stem Cell and Cancer Biology, Swammerdam Institute for Life Sciences, University of Amsterdam, Science Park 904, 1098 XH, Amsterdam, the Netherlands. r.vanamerongen@uva.nl.ORCID 0000-0002-8808-2092
Mohamed Bentires-AljLaboratory of Tumor Heterogeneity, Metastasis and Resistance, Department of Biomedicine, University of Basel and University Hospital of Basel, Basel, Switzerland.ORCID 0000-0001-6344-1127
Antonius L van BoxtelDevelopmental, Stem Cell and Cancer Biology, Swammerdam Institute for Life Sciences, University of Amsterdam, Science Park 904, 1098 XH, Amsterdam, the Netherlands.ORCID 0009-0006-6649-3807
Robert B ClarkeManchester Breast Centre, Division of Cancer Sciences, School of Medical Sciences, University of Manchester, Manchester, UK.ORCID 0000-0001-5407-3123
Silvia FreInstitut Curie, Genetics and Developmental Biology Department, PSL Research University, CNRS UMR3215, U93475248, InsermParis, France.ORCID 0000-0002-7209-7636
Eva Gonzalez SuarezTransformation and Metastasis Laboratory, Molecular Oncology, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.ORCID 0000-0003-0858-8171
Richard IggoINSERM U1312, University of Bordeaux, 33076, Bordeaux, France.ORCID 0000-0002-8822-9111
Martin JechlingerCell Biology and Biophysics Department, EMBL, Heidelberg, Germany.ORCID 0000-0002-3710-4466
Jos JonkersDivision of Molecular Pathology, Oncode Institute, Netherlands Cancer Institute, Plesmanlaan 121, 1066CX, Amsterdam, The Netherlands.ORCID 0000-0002-9264-9792
Marja L MikkolaInstitute of Biotechnology, HiLIFE Helsinki Institute of Life Science, University of Helsinki, P.O.B. 56, 00014, Helsinki, Finland.ORCID 0000-0002-9890-3835
Zuzana Sumbalova KoledovaDepartment of Histology and Embryology, Faculty of Medicine, Masaryk University, Kamenice 5, 625 00, Brno, Czech Republic.ORCID 0000-0002-9333-1399
Therese SørlieDepartment of Cancer Genetics, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway.ORCID 0000-0002-5995-2319
Maria dM VivancoCancer Heterogeneity Lab, CIC bioGUNE, Basque Research and Technology Alliance, BRTA, Technological Park Bizkaia, 48160, Derio, Spain.ORCID 0000-0002-9540-247X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

On 8 December 2022 the organizing committee of the European Network for Breast Development and Cancer labs (ENBDC) held its fifth annual Think Tank meeting in Amsterdam, the Netherlands. Here, we embraced the opportunity to look back to identify the most prominent breakthroughs of the past ten years and to reflect on the main challenges that lie ahead for our field in the years to come. The outcomes of these discussions are presented in this position paper, in the hope that it will serve as a summary of the current state of affairs in mammary gland biology and breast cancer research for early career researchers and other newcomers in the field, and as inspiration for scientists and clinicians to move the field forward.

Indexed as

Breast NeoplasmsMammary Glands, HumanBiologyBreastFemaleHumansBreast cancer heterogeneityLineage tracingModel systemsPrevention and early detectionSingle cell analysesTreatment and recurrence

Identifiers

PMID37450065
PMCPMC10349020

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.