ArticleHypertension research : official journal of the Japanese Society of Hypertension2024
Nocturnal systolic blood pressure dipping and progression of chronic kidney disease.
Article in Hypertension research : official journal of the Japanese Society of Hypertension, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Unlocking the potential of circadian biology for cardiovascular health.Physiological reviews · 2026Review
- Diurnal Blood Pressure Profiles and Hypertension-Mediated Organ Damage in Early Stages of Chronic Kidney Disease.Life (Basel, Switzerland) · 2025Article
- Hypertension burden in CKD: is nocturnal hypertension the primary culprit?Clinical kidney journal · 2025Review
- Clinical Impact of Blood Pressure Variability in Kidney Transplant Patients: A Systematic Review and Meta-Analysis.Life (Basel, Switzerland) · 2025Review
- Joint effects of sodium intake and circadian rhythm of urinary sodium excretion on prognosis of chronic kidney disease: a prospective study.Therapeutic advances in chronic disease · 2025Article
- Glomerular pressure and tubular oxygen supply: a critical dual target for renal protection.Hypertension research : official journal of the Japanese Society of Hypertension · 2024Review
- Hypertension and Cardiovascular Risk Among Children with Chronic Kidney Disease.Current hypertension reports · 2024Review
- Commentary on 'the predictors of daytime blood pressure, nighttime blood pressure, and nocturnal dipping in patients with chronic kidney disease.Hypertension research : official journal of the Japanese Society of Hypertension · 2024Article
- Chronic Kidney Disease Progression-A Challenge.Biomedicines · 2024Review
- Development and Validation of a Deep Learning Model for Prediction of Adult Physiological Deterioration.Critical care explorations · 2024Article
- While You Are Sleeping: Marital Ambivalence and Blunted Nocturnal Blood Pressure.International journal of environmental research and public health · 2024Article
- Risk Factors of Chronic Kidney Disease Progression: Between Old and New Concepts.Journal of clinical medicine · 2024Review
- Prognostic Value of Blood Pressure Rhythmicity for Estimated Glomerular Filtration Rate in Male Hypertensive Patients Aged 55 and Older.Kidney diseases (Basel, Switzerland)Article
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The relationship between declining nocturnal blood pressure (BP) and adverse cardiovascular outcomes is well-recognized. However, the relationship between diurnal BP profile and the risk of chronic kidney disease (CKD) progression is unclear. Herein, we examined the association between nocturnal systolic SBP (SBP) dipping and CKD progression in 1061 participants at the Cardiovascular and Metabolic Disease Etiology Research Center-High Risk (CMERC-HI). The main exposure was diurnal systolic BP (SBP) profile and diurnal SBP difference ([nighttime SBP-daytime SBP] × 100/daytime SBP). The primary outcome was CKD progression, defined as a composite of ≥ a 50% decline in the estimated glomerular filtration rate from baseline or the initiation of kidney replacement therapy. During 4749 person-years of follow-up (median, 4.8 years), the composite outcome occurred in 380 (35.8%) participants. Compared to dippers, the hazard ratios (HRs) for the risk of adverse kidney outcomes were 1.02 (95% confidence interval [CI], 0.64-1.62), 1.30 (95% CI, 1.02-1.66), and 1.40 (95% CI, 1.03-1.90) for extreme dipper, non-dipper, and reverse dipper, respectively. In a continuous modeling, a 10% increase in diurnal SBP difference was associated with a 1.21-fold (95% CI, 1.07-1.37) higher risk of CKD progression. Thus, decreased nocturnal SBP decline was associated with adverse kidney outcomes in patients with CKD. Particularly, patients with non-dipping and reverse dipping patterns were at higher risk for CKD progression than those with a dipping pattern.
Indexed as
Identifiers
37452154What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.