Metformin × body weight & composition

TrialDiabetologia2023

Metformin for the prevention of diabetes among people with HIV and either impaired fasting glucose or impaired glucose tolerance (prediabetes) in Tanzania: a Phase II randomised placebo-controlled trial.

Anupam Garrib et al.PubMed ↗Full text ↗Publisher ↗

What the trial testedrandomised · 364 people · 2023

Randomised comparison

Probably lowered body weight & composition

−1.47kg−2.58 to −0.35

As reported

difference −1.47 kg, 95% CI −2.58 to −0.35

One number in the abstract

the abstract, start to end

the mean difference in weight was -1.47 kg (95% CI -2.58, -0.35).

← favours treatmentfavours comparator →
could be chance
Body weight & composition
−1.47−2.58 to −0.35
MetforminBody weight & composition

Metformin × body weight & compositionhelps?mixed

unlikelylikely
0.500.50 without it
← favours treatmentfavours comparator →
this papermore certainless certain
1 / 5

7 papers cite it

2023
2024
2025
2026
this paperpooled itcites it

The trial

Full record →Abstract, authors, funding and every citing paper · PMID 37460828