Evidence map›Paper›PMID 37461494›Full record

ArticleResearch square2023

Drosophila UBE3A regulates satiety signaling through the Piezo mechanosensitive ion channel.

Benjamin Geier, Logan Neely, Eli Coronado, Lawrence T Reiter

Open access · greenAbstract readPreprint
In one paragraph

Article in Research square, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Benjamin GeierUniversity of Tennessee Health Science Center.
Logan NeelyUniversity of Tennessee Health Science Center.
Eli CoronadoUniversity of Tennessee Health Science Center.
Lawrence T ReiterUniversity of Tennessee Health Science Center.
University of Tennessee Health Science Center · US

Funding

Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
The role of UBE3A in gliopathic seizuresR01NS115776 · NINDS · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI REITER, LAWRENCE T, ZAKHARENKO, STANISLAV S · 2020 to 2024
$2.0M
NIH HHS P40 OD018537NINDS NIH HHS R01 NS115776
6 · The paper itself

Abstract

Angelman syndrome (AS) is a rare neurogenetic disorder characterized by developmental delays, speech impairments, ataxic movements, and in some cases, hyperphagic feeding behavior. Loss of function mutations, loss of expression from the maternal allele or absence of maternal UBE3A result in AS. Recent studies have established a connection between

Identifiers

PMID37461494
PMCPMC10350227
OpenAlexW4382931449

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.