Evidence map›Paper›PMID 37467022›Full record

ArticleAmerican journal of physiology. Endocrinology and metabolism2023

Inhibition of protein kinase C-α and activation of ezrin by

Yiran Han, Shanthi Srinivasan, C Chris Yun

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Endocrinology and metabolism, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Regulation of the intestinal NaAmerican journal of physiology. Cell physiology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Yiran HanGastroenterology Research, Atlanta Veterans Administration Medical Center, Decatur, Georgia, United States.
Shanthi SrinivasanGastroenterology Research, Atlanta Veterans Administration Medical Center, Decatur, Georgia, United States.
C Chris YunGastroenterology Research, Atlanta Veterans Administration Medical Center, Decatur, Georgia, United States.ORCID 0000-0002-5518-9870
United States Department of Veterans Affairs · US

Funding

Winship Cancer Institute Cancer Center Support GrantP30CA138292 · NCI · EMORY UNIVERSITY · PI Ragini Reiney Kudchadkar · 2009 to 2026
$47.5M
Role of Na+/H+ exchanger in diabetic diarrheaI01BX004459 · VA · VETERANS HEALTH ADMINISTRATION · PI YUN, CHANGHYON CHRIS · 2020 to 2024
–
BLRD VA I01 BX004459NCI NIH HHS P30 CA138292
6 · The paper itself

Abstract

Gastrointestinal (GI) complications, including diarrhea, constipation, and gastroparesis, are common in patients with diabetes. Dysregulation of the Na

Indexed as

Diabetes Mellitus, ExperimentalDiabetes Mellitus, Type 2MetforminAnimalsConstipationDiarrheaEzrinHumansLactobacillus acidophilusMiceProtein Kinase C-alphaSodium-Hydrogen Exchanger 3Sodium-Hydrogen ExchangersEzrinMetforminPrkca protein, mouseProtein Kinase C-alphaSodium-Hydrogen Exchanger 3Sodium-Hydrogen ExchangersdiabetesezrinNHE3protein kinase C

Identifiers

PMID37467022
PMCPMC10511175
OpenAlexW4384664707

What Socratic holds

Texttitle and abstract
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.