ArticleNature2023
An atlas of healthy and injured cell states and niches in the human kidney.
Abstract read
In one paragraph
Article in Nature, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 504 papers.
0numbers the graph read from it
0cells of the map it votes in
504citing papers in PubMed
–field-weighted citation impact
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
504 citing papers in PubMed.
- Metabolic surgery mitigates early kidney injury in obese youth with diabetes by suppressing mTORC1/JAK/STAT signaling.The Journal of clinical investigation · 2026Trial
- Urinary clusterin as a biomarker of human kidney disease progression and response to the endothelin receptor antagonist atrasentan: An exploratory analysis from the SONAR trial.Nature communications · 2026Trial
- Integrative multi-omics analysis identifies VCAN and ESM1 as candidate cell-type-associated biomarkers of NET-related glomerular injury in diabetic kidney disease.Renal failure · 2026Article
- Integrated bioinformatics analysis uncovers TNFSF10 as a key panoptosis-related gene in diabetic tubular injury.Renal failure · 2026Article
- Epigallocatechin-3-gallate attenuates oxidative stress and apoptosis in podocytes of focal segmental glomerulosclerosis.Renal failure · 2026Article
- Mitochondrial dysfunction of renal tubular epithelial cells in chronic kidney disease-associated fibrosis: from organelle homeostasis to multicellular remodeling.Molecular biology reports · 2026Review
- The landscape of allele-specific expression in human kidneys.Science advances · 2026Article
- Kidney Transcriptome Sequencing Improves Molecular Diagnosis and Reveals Splicing Complexity Across the Alport Spectrum.Kidney international reports · 2026Article
- Single-Nucleus Transcriptomic Atlas Reveals Disease-Associated Cellular States in Human Glomerular Diseases.Kidney international reports · 2026Article
- Spatial Transcriptomics and Mechanisms of Immune Checkpoint Inhibitor-Associated Interstitial Nephritis.Kidney international reports · 2026Article
- Maternal kidney adaptation and function in pregnancy: review and perspectives.Function (Oxford, England) · 2026Review
- Effects of semaglutide on kidney disease in type 2 diabetes: a randomized placebo-controlled trial.Nature medicine · 2026Article
- T-Cell Remodeling in Renal Fibrosis: From Acute Injury to Chronic Kidney Disease.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- A cross-species single-cell kidney epigenome atlas reveals epithelial-dominant aging-like states in disease.Nature aging · 2026Article
- The role of senescence in kidney ageing, injury and fibrosis.Nature reviews. Nephrology · 2026Review
- New perspectives on thick ascending limb function and cell types.Kidney international · 2026Review
- Semi-metric optimal transport enables robust spatial multi-omics integration.Research square · 2026Article
- spaGFM is a scalable graph foundation model for spatial transcriptomics analyses.Research square · 2026Article
- Review
- HNF4A maintains proximal tubule identity and limits injury-associated cell states in the adult mouse kidney.bioRxiv : the preprint server for biology · 2026Article
444 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
51 authors.
Blue B Lake *Department of Bioengineering, University of California, San Diego, La Jolla, CA, USA.
Rajasree Menon *Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.
Seth Winfree *Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE, USA.ORCID 0000-0002-2396-5871
Qiwen Hu *Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.ORCID 0000-0003-2798-919X
Ricardo Melo Ferreira *Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA.ORCID 0000-0003-2063-9744
Kian Kalhor *Department of Bioengineering, University of California, San Diego, La Jolla, CA, USA.
Daria BarwinskaDepartment of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA.ORCID 0000-0002-0776-3030
Edgar A OttoDepartment of Internal Medicine, Division of Nephrology, University of Michigan, Ann Arbor, MI, USA.
Michael FerkowiczDepartment of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA.
Dinh DiepDepartment of Bioengineering, University of California, San Diego, La Jolla, CA, USA.
Nongluk PlongthongkumDepartment of Bioengineering, University of California, San Diego, La Jolla, CA, USA.
Amanda KnotenDepartment of Medicine, Washington University School of Medicine, St Louis, MO, USA.
Sarah UrataDepartment of Bioengineering, University of California, San Diego, La Jolla, CA, USA.
Laura H MarianiDepartment of Internal Medicine, Division of Nephrology, University of Michigan, Ann Arbor, MI, USA.
Abhijit S NaikDepartment of Internal Medicine, Division of Nephrology, University of Michigan, Ann Arbor, MI, USA.
Sean EddyDepartment of Internal Medicine, Division of Nephrology, University of Michigan, Ann Arbor, MI, USA.
Bo ZhangDepartment of Medicine, Washington University School of Medicine, St Louis, MO, USA.
Yan WuDepartment of Bioengineering, University of California, San Diego, La Jolla, CA, USA.
Diane SalamonDepartment of Medicine, Washington University School of Medicine, St Louis, MO, USA.
James C WilliamsDepartment of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA.
Xin WangDepartment of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.
Karol S BalderramaBroad Institute of Harvard and MIT, Cambridge, MA, USA.
Paul J HooverBroad Institute of Harvard and MIT, Cambridge, MA, USA.
Evan MurrayBroad Institute of Harvard and MIT, Cambridge, MA, USA.
Jamie L MarshallBroad Institute of Harvard and MIT, Cambridge, MA, USA.
Teia NoelBroad Institute of Harvard and MIT, Cambridge, MA, USA.
Anitha VijayanDepartment of Medicine, Washington University School of Medicine, St Louis, MO, USA.
Austin HartmanNew York Genome Center, New York, NY, USA.
Fei ChenBroad Institute of Harvard and MIT, Cambridge, MA, USA.ORCID 0000-0003-2308-3649
Sushrut S WaikarSection of Nephrology, Boston University School of Medicine and Boston Medical Center, Boston, MA, USA.ORCID 0000-0003-4004-326X
Sylvia E RosasKidney and Hypertension Unit, Joslin Diabetes Center, Boston, MA, USA.
Francis P WilsonDepartment of Medicine, Yale University School of Medicine, New Haven, CT, USA.ORCID 0000-0002-2633-2412
Paul M PalevskyDepartment of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.ORCID 0000-0002-7334-5400
Krzysztof KirylukDepartment of Medicine, Columbia University, New York, NY, USA.
John R SedorLerner Research and Glickman Urology and Kidney Institutes, Cleveland Clinic, Cleveland, OH, USA.
Robert D TotoDepartment of Internal Medicine, UT Southwestern Medical Center, Dallas, TX, USA.
Chirag R ParikhDivision of Nephrology, Johns Hopkins School of Medicine, Baltimore, MD, USA.
Eric H KimDepartment of Surgery, Washington University School of Medicine, St Louis, MO, USA.ORCID 0000-0002-0284-8342
Rahul SatijaNew York Genome Center, New York, NY, USA.ORCID 0000-0001-9448-8833
Anna GrekaBroad Institute of Harvard and MIT, Cambridge, MA, USA.
Evan Z MacoskoBroad Institute of Harvard and MIT, Cambridge, MA, USA.ORCID 0000-0002-2794-5165
Peter V KharchenkoDepartment of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-6036-5875
Joseph P GautDepartment of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA.
Jeffrey B HodginDepartment of Pathology, University of Michigan, Ann Arbor, MI, USA.
KPMP Consortium
Michael T EadonDepartment of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA. meadon@iupui.edu.ORCID 0000-0003-3066-2876
Pierre C DagherDepartment of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA. pdaghe2@iu.edu.ORCID 0000-0003-3321-5561
Tarek M El-AchkarDepartment of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA. telachka@iu.edu.ORCID 0000-0003-4645-3614
Kun ZhangDepartment of Bioengineering, University of California, San Diego, La Jolla, CA, USA. kzhang@bioeng.ucsd.edu.ORCID 0000-0002-7596-5224
Matthias KretzlerDepartment of Internal Medicine, Division of Nephrology, University of Michigan, Ann Arbor, MI, USA. kretzler@med.umich.edu.ORCID 0000-0003-4064-0582
Sanjay JainDepartment of Medicine, Washington University School of Medicine, St Louis, MO, USA. sanjayjain@wustl.edu.ORCID 0000-0003-2804-127X
Funding
Washington University Center for Cellular ImagingP30CA091842 · NCI · WASHINGTON UNIVERSITY · PI TIMOTHY J. EBERLEIN · 2001 to 2026
$128.0MYale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9MTransform Dissemination and Implementation Science in CTSA ProgramsUL1TR002319 · NCATS · UNIVERSITY OF WASHINGTON · PI John K. Amory · 2017 to 2026
$100.0MWU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8MSPECIAL ASSAY COREP30DK036836 · NIDDK · JOSLIN DIABETES CENTER · PI ROHIT N. KULKARNI · 1986 to 2026
$50.5MSTONE FORMATION IN GENETIC HYPERCALCIURIAP01DK056788 · NIDDK · UNIVERSITY OF CHICAGO · PI WORCESTER, ELAINE M · 2000 to 2021
$22.5MConProject-002U2CDK114886 · NIDDK · UNIVERSITY OF WASHINGTON · PI HIMMELFARB, JONATHAN, IYENGAR, SRINIVAS RAVI V · 2017 to 2021
$21.0MTraining Program in Clinical & Translationa Research in Human Glomerular DiseaseU54DK083912 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KRETZLER, MATTHIAS · 2009 to 2023
$20.3MPROBE DELIVERY COREP30DK079312 · NIDDK · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI MOLITORIS, BRUCE A · 2007 to 2021
$17.1MUniversity of Michigan O'Brien Kidney Translational Core CenterP30DK081943 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI PENNATHUR, SUBRAMANIAM · 2008 to 2022
$12.9MKPMP Kidney Mapping and Atlas Project (KMAP)U01DK133090 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Jonathan Himmelfarb, Matthias Kretzler · 2022 to 2026
$10.4MToward a human adult brain cell atlas with single-cell technologiesU01MH114828 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CHUN, JEROLD, REN, BING · 2018 to 2022
$8.7MNCATS NIH HHS UL1 TR001863NCATS NIH HHS UL1 TR002319NCATS NIH HHS UL1 TR002345NCI NIH HHS P30 CA091842NCI NIH HHS UH3 CA246632NHLBI NIH HHS U54 HL145608NIDDK NIH HHS K08 DK107864NIDDK NIH HHS K23 DK125529NIDDK NIH HHS P01 DK056788NIDDK NIH HHS P30 DK036836NIDDK NIH HHS P30 DK079312NIDDK NIH HHS P30 DK081943NIDDK NIH HHS R01 DK111651NIDDK NIH HHS U01 DK114907NIDDK NIH HHS U01 DK114923NIDDK NIH HHS U01 DK114933NIDDK NIH HHS U01 DK133090NIDDK NIH HHS U2C DK114886NIDDK NIH HHS U54 DK083912NIDDK NIH HHS U54 DK134301NIDDK NIH HHS U54 DK137328NIDDK NIH HHS UG3 DK114861NIDDK NIH HHS UH3 DK114861NIDDK NIH HHS UH3 DK114866NIDDK NIH HHS UH3 DK114870NIDDK NIH HHS UH3 DK114907NIDDK NIH HHS UH3 DK114908NIDDK NIH HHS UH3 DK114915NIDDK NIH HHS UH3 DK114923NIDDK NIH HHS UH3 DK114926NIDDK NIH HHS UH3 DK114933NIH HHS S10 OD026929NIMH NIH HHS U01 MH114828
Abstract
Understanding kidney disease relies on defining the complexity of cell types and states, their associated molecular profiles and interactions within tissue neighbourhoods
Indexed as
Gene Expression ProfilingKidneyKidney DiseasesSingle-Cell AnalysisTranscriptomeCase-Control StudiesCell NucleusHumansImaging, Three-Dimensional
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What Socratic holds
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LicenceCC BY
Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.