ArticleNature2023
Organization of the human intestine at single-cell resolution.
Open access · hybridAbstract read
In one paragraph
Article in Nature, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 224 papers.
0numbers the graph read from it
0cells of the map it votes in
224citing papers in PubMed
43.7field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
224 citing papers in PubMed, 285 citations in OpenAlex.
- The gut microbiota as a regulator of intestinal stem-cell fate: bacterial and fungal control of differentiation and regeneration.Gut microbes · 2026Review
- Notch receptors involved in the choice between intestinal secretory and enterocytes and differentiation of Bestrophin4 cells.Developmental biology · 2026Article
- Diverse infections transcriptionally reprogram the intestinal epithelium and epithelial-immune cell interactions.Nature immunology · 2026Article
- Regional organization of nutrient absorption across the small intestine.Nature reviews. Gastroenterology & hepatology · 2026Review
- Single-cell analysis of chromatin accessibility in the human intestine identifies regulatory programs and clarifies genetic associations in Crohn's disease.Nature genetics · 2026Article
- Multiscale harmonization, semantic integration, and immersive exploration of single-cell data in support of novel biological insights.bioRxiv : the preprint server for biology · 2026Article
- Article
- Peripheral non-invasive focused ultrasound alleviates constipation by reducing gastrointestinal inflammation.Experimental physiology · 2026Article
- Global GPR75 deficiency protects against diet-induced obesity through central and peripheral mechanisms.Molecular metabolism · 2026Article
- Spatial Logic and Evolutionary Innovation in Human Placentation.bioRxiv : the preprint server for biology · 2026Article
- Building and regenerating intestines by manipulating intestinal stem cells.Nature reviews. Gastroenterology & hepatology · 2026Review
- Cell-type specific analyses in blood and gut identify cis-eQTL matching 140 IBD risk loci and entrectinib as repurposing candidate.Nature communications · 2026Article
- Iterative multiplex imaging cytometry for cross-species analyses of in situ tissue leukocytes.Journal of immunological methods · 2026Article
- Article
- HuBMAP Data Portal: a resource for multimodal spatial and single-cell data of healthy human tissues.ArXiv · 2026Article
- BEST4⁺ cells: a potential hub of intestinal ion transport and diarrhea manipulation.Advanced biotechnology · 2026Review
- Tissue and cellular spatiotemporal dynamics in colon aging.Nature biotechnology · 2026Article
- Spatium: A Protein Language Foundation Model for Spatial Proteomics.bioRxiv : the preprint server for biology · 2026Article
- Human genetics across levels of biological organization.Nature reviews. Genetics · 2026Review
- Epithelial Chloride and Bicarbonate Transport in Intestinal Barrier Failure: A Molecular Target-Validation Assessment of CFTR and SLC26A3/DRA in Inflammatory Bowel Disease.International journal of molecular sciences · 2026Review
164 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
33 authors at 6 institutions in 2 countries.
John W Hickey *Department of Pathology, Stanford School of Medicine, Stanford, CA, USA.ORCID 0000-0001-9961-7673
Winston R Becker *Department of Genetics, Stanford School of Medicine, Stanford, CA, USA.ORCID 0000-0001-7876-5060
Stephanie A Nevins *Department of Genetics, Stanford School of Medicine, Stanford, CA, USA.
Aaron HorningDepartment of Genetics, Stanford School of Medicine, Stanford, CA, USA.
Almudena Espin PerezDepartment of Biomedical Data Science, Stanford School of Medicine, Stanford, CA, USA.
Chenchen ZhuDepartment of Genetics, Stanford School of Medicine, Stanford, CA, USA.ORCID 0000-0003-2165-9456
Bokai ZhuDepartment of Pathology, Stanford School of Medicine, Stanford, CA, USA.
Bei WeiDepartment of Genetics, Stanford School of Medicine, Stanford, CA, USA.
Roxanne ChiuDepartment of Genetics, Stanford School of Medicine, Stanford, CA, USA.
Derek C ChenDepartment of Genetics, Stanford School of Medicine, Stanford, CA, USA.ORCID 0000-0001-9652-4885
Daniel L CotterDepartment of Genetics, Stanford School of Medicine, Stanford, CA, USA.ORCID 0000-0002-1625-3083
Edward D EsplinDepartment of Genetics, Stanford School of Medicine, Stanford, CA, USA.
Annika K WeimerDepartment of Genetics, Stanford School of Medicine, Stanford, CA, USA.ORCID 0000-0001-9944-8769
Chiara CaraccioDepartment of Pathology, Stanford School of Medicine, Stanford, CA, USA.ORCID 0000-0002-3580-1348
Vishal VenkataraamanDepartment of Pathology, Stanford School of Medicine, Stanford, CA, USA.
Christian M SchürchDepartment of Pathology, Stanford School of Medicine, Stanford, CA, USA.ORCID 0000-0002-1792-1768
Sarah BlackDepartment of Pathology, Stanford School of Medicine, Stanford, CA, USA.
Maria BrbićDepartment of Computer Science, Stanford University, Stanford, CA, USA.ORCID 0000-0002-1120-1778
Kaidi CaoDepartment of Computer Science, Stanford University, Stanford, CA, USA.
Shuxiao ChenDepartment of Statistics and Data Science, University of Pennsylvania, Pennsylvania, PA, USA.
Weiruo ZhangDepartment of Biomedical Data Science, Stanford School of Medicine, Stanford, CA, USA.ORCID 0000-0003-3680-7562
Emma MonteDepartment of Genetics, Stanford School of Medicine, Stanford, CA, USA.
Nancy R ZhangDepartment of Statistics and Data Science, University of Pennsylvania, Pennsylvania, PA, USA.ORCID 0000-0002-0880-5749
Zongming MaDepartment of Statistics and Data Science, University of Pennsylvania, Pennsylvania, PA, USA.ORCID 0000-0003-2401-0177
Jure LeskovecDepartment of Computer Science, Stanford University, Stanford, CA, USA.
Zhengyan ZhangDepartment of Surgery, Washington University, St Louis, MO, USA.ORCID 0000-0003-4979-9573
Shin LinDepartment of Medicine, University of Washington, Seattle, WA, USA.
Teri LongacreDepartment of Pathology, Stanford School of Medicine, Stanford, CA, USA.
Sylvia K PlevritisDepartment of Biomedical Data Science, Stanford School of Medicine, Stanford, CA, USA.
Yiing LinDepartment of Surgery, Washington University, St Louis, MO, USA.ORCID 0000-0002-0317-7608
Garry P NolanDepartment of Pathology, Stanford School of Medicine, Stanford, CA, USA. gnolan@stanford.edu.ORCID 0000-0002-8862-9043
William J GreenleafDepartment of Genetics, Stanford School of Medicine, Stanford, CA, USA. wjg@stanford.edu.ORCID 0000-0003-1409-3095
Michael SnyderDepartment of Genetics, Stanford School of Medicine, Stanford, CA, USA. mpsnyder@stanford.edu.ORCID 0000-0003-0784-7987
Stanford Medicine · USUniversity of Pennsylvania · USStanford University · USWashington University in St. Louis · USÉcole Polytechnique Fédérale de Lausanne · CHUniversity of Washington · US
Funding
Using a tonsil organoid system to probe conditions for the induction of protective antibody and T cell responses to influenza.U19AI057229 · NIAID · STANFORD UNIVERSITY · PI Mark Morris Davis · 2003 to 2026
$88.5MVACCINE INDUCED IMMUNITY IN THE YOUNG AND AGEDU19AI057266 · NIAID · EMORY UNIVERSITY · PI Rafi Ahmed · 2003 to 2026
$81.7MStanford Mendelian Genomics Research CenterU01HG011762 · NHGRI · STANFORD UNIVERSITY · PI Jonathan Adam Bernstein, Stephen Montgomery · 2021 to 2026
$16.7MSpecial EquipmentP50HG007735 · NHGRI · STANFORD UNIVERSITY · PI CHANG, HOWARD Y · 2014 to 2018
$15.2MStanford Tissue Mapping CenterU54HG010426 · NHGRI · STANFORD UNIVERSITY · PI NOLAN, GARRY P, SNYDER, MICHAEL P. · 2018 to 2021
$5.1MCancer-Translational Nanotechnology Training Program (Cancer-TNT)T32CA196585 · NCI · STANFORD UNIVERSITY · PI FELSHER, DEAN W, RAO, JIANGHONG · 2015 to 2019
$1.8MCancer Research UK 27145NCI NIH HHS T32 CA196585NHGRI NIH HHS P50 HG007735NHGRI NIH HHS U01 HG011762NHGRI NIH HHS U54 HG010426NIAID NIH HHS U19 AI057229NIAID NIH HHS U19 AI057266
Abstract
The intestine is a complex organ that promotes digestion, extracts nutrients, participates in immune surveillance, maintains critical symbiotic relationships with microbiota and affects overall health
Indexed as
IntestinesSingle-Cell AnalysisCell DifferentiationChromatinEpithelial CellsGene Expression RegulationHumansIntestinal MucosaSingle-Cell Gene Expression AnalysisChromatin
Identifiers
What Socratic holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.