ArticleArthritis research & therapy2023
Chronic neck pain is associated with increased mortality in individuals with osteoarthritis: results from the NHANES database prospective cohort study.
Article in Arthritis research & therapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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5 citing papers in PubMed, 6 citations in OpenAlex.
- Chronic pain and mortality risk among middle-age and older Japanese: the Shika town cohort study.Pain reports · 2025Article
- Evaluating anthropometric indices of obesity for early osteoarthritis detection: focus on body fat percentage and relative fat mass.Clinical rheumatology · 2025Article
- Association between neutrophil-lymphocyte ratio and all-cause and cardiovascular mortality in osteoarthritis patients from the NHANES 1999-2018 cohort.Scientific reports · 2025Article
- Association of cardiovascular health with morbidity and mortality among U.S. adults with osteoarthritis: a population-based study.BMC public health · 2025Article
- Prevalence of Musculoskeletal Disorders in Heavy Vehicle Drivers and Office Workers: A Comparative Analysis Using a Machine Learning Approach.Healthcare (Basel, Switzerland) · 2024Article
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5 authors at 2 institutions in 1 country.
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Abstract
backgroundNeck pain (NP) is a common symptom reported in the elderly. However, no study has examined the relationship between NP and osteoarthritis (OA) so far, and this study aimed to investigate the association of neck pain with the prevalence and mortality of OA.
methodsA total of 5965 participants were included in this cohort study based on the National Health and Nutrition Examination Survey data set of the USA (NHANES). Death outcomes follow-up information was ascertained by linkage to National Death Index (NDI). The association between NP and OA was studied by multi-various logistic regression models after adjusting for potential confounding factors. Cox proportional hazards models were used to elucidate the relationship between NP and all-cause mortality in OA patients.
resultsAmong all participants, 8.18% had osteoarthritis, and 5.92% suffered from neck pain. Neck pain was associated with osteoarthritis [1.932 (1.232, 3.028), p < 0.01], which still reminded significant after adjustments [2.519 (1.325, 4.788), p < 0.01] and stratified analysis by sex, race, and smoke status. In OA patients, chronic neck pain (over 1 year) was significantly associated with higher risks of all-cause mortality before [2.94 (1.61, 5.37), p < 0.01] and after adjustment [3.30 (1.23, 45.85), p < 0.05].
conclusionNeck pain was strongly associated with osteoarthritis. Moreover, chronic neck pain over 1 year significantly increased the mortality of OA patients. Our study demonstrates the need to screen osteoarthritis in the neck pain population and select a more appropriate treatment strategy promptly for those patients.
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