Evidence map›Paper›PMID 37470216›Full record

ArticleAntioxidants & redox signaling2023

Nicotinamide Adenine Dinucleotide Phosphate Oxidase Promotes Glioblastoma Radiation Resistance in a Phosphate and Tensin Homolog-Dependent Manner.

Kirsten Ludwig, Janel E Le Belle, Sree Deepthi Muthukrishnan, Jantzen Sperry, Michael Condro, Erina Vlashi, Frank Pajonk, Harley I Kornblum

Open access · greenAbstract read
In one paragraph

Article in Antioxidants & redox signaling, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Kirsten LudwigThe Intellectual and Developmental Disabilities Research Center and the Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.ORCID 0000-0003-0255-9732
Janel E Le BelleThe Intellectual and Developmental Disabilities Research Center and the Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.
Sree Deepthi MuthukrishnanThe Intellectual and Developmental Disabilities Research Center and the Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.
Jantzen SperryThe Intellectual and Developmental Disabilities Research Center and the Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.
Michael CondroThe Intellectual and Developmental Disabilities Research Center and the Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.
Erina VlashiDepartment of Radiation Oncology, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.ORCID 0000-0002-2505-3577
Frank PajonkDepartment of Radiation Oncology, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.
Harley I KornblumThe Intellectual and Developmental Disabilities Research Center and the Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.ORCID 0000-0002-3779-4540
Neurobehavioral Systems · USUniversity of California, Los Angeles · US

Funding

UCLA SPORE in Brain CancerP50CA211015 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Yvonne Yu-Hsuan Chen · 2017 to 2026
$25.2M
Use of CTEP portfolio compounds to counteract phenotype conversion in GBMR01CA260886 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Frank Pajonk · 2022 to 2026
$2.6M
Neural Progenitor Genes and Brain TumorsR01NS052563 · NINDS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI KORNBLUM, HARLEY IAN · 2006 to 2015
$2.4M
Utilizing Radiation-Induced Multi-potency to Increase the Efficacy of RadiotherapyR01CA281682 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Frank Pajonk · 2023 to 2026
$2.0M
Glioblastoma, Glioblastoma Stem Cells and RadiotherapyR01CA200234 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI PAJONK, FRANK · 2016 to 2020
$1.8M
NCI NIH HHS P50 CA211015NCI NIH HHS R01 CA200234NCI NIH HHS R01 CA260886NCI NIH HHS R01 CA281682NINDS NIH HHS R01 NS052563
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Brain NeoplasmsGlioblastomaHumansHypoxiaNADPNADPH OxidasesPhosphatesReactive Oxygen SpeciesTensinsNADPNADPH OxidasesPhosphatesReactive Oxygen SpeciesTensinsglioblastomagliomahypoxiaNADPH oxidasep22phoxPTENradiation

Identifiers

PMID37470216
PMCPMC10775910
OpenAlexW4384820884

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.