Evidence map›Paper›PMID 37470227›Full record

ArticleeLife2023

New hypotheses of cell type diversity and novelty from orthology-driven comparative single cell and nuclei transcriptomics in echinoderms.

Anne Meyer, Carolyn Ku, William L Hatleberg, Cheryl A Telmer, Veronica Hinman

Open access · goldAbstract read
In one paragraph

Article in eLife, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 29 citations in OpenAlex.

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  10. International journal of molecular sciences · 2024
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Anne MeyerDepartment of Biological Sciences, Carnegie Mellon University, Pittsburgh, United States.ORCID 0000-0003-2287-7316
Carolyn KuDepartment of Biological Sciences, Carnegie Mellon University, Pittsburgh, United States.
William L HatlebergDepartment of Biological Sciences, Carnegie Mellon University, Pittsburgh, United States.ORCID 0000-0002-0423-7123
Cheryl A TelmerDepartment of Biological Sciences, Carnegie Mellon University, Pittsburgh, United States.ORCID 0000-0002-7649-3134
Veronica HinmanDepartment of Biological Sciences, Carnegie Mellon University, Pittsburgh, United States.ORCID 0000-0003-3414-1357
Carnegie Mellon University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cell types are the building blocks of metazoan biodiversity and offer a powerful perspective for inferring evolutionary phenomena. With the development of single-cell transcriptomic techniques, new definitions of cell types are emerging. This allows a conceptual reassessment of traditional definitions of novel cell types and their evolution. Research in echinoderms, particularly sea star and sea urchin embryos has contributed significantly to understanding the evolution of novel cell types, through the examination of skeletogenic mesenchyme and pigment cells, which are found in sea urchin larvae, but not sea star larvae. This paper outlines the development of a gene expression atlas for the bat sea star,

Indexed as

EchinodermataTranscriptomeAnimalsCell NucleusGene Expression Regulation, DevelopmentalSea UrchinsStarfishcell typedevelopmental biologyevolutionary biologynonenoveltyPatiria miniatasingle nucleitranscriptomics

Identifiers

PMID37470227
PMCPMC10396339
OpenAlexW4384820185

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.