Evidence map›Paper›PMID 37474258›Full record

ArticleRNA (New York, N.Y.)2023

Multiple domains of the integral KREPA3 protein are critical for the structure and precise functions of RNA editing catalytic complexes in

Brittney Davidge, Suzanne M McDermott, Jason Carnes, Isaac Lewis, Maxwell Tracy, Kenneth D Stuart

Abstract read
In one paragraph

Article in RNA (New York, N.Y.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Deep mutational scanning of the RNase III-like domain inFrontiers in cellular and infection microbiology · 2024
    Article
  5. Article
  6. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Brittney DavidgeCenter for Global Infectious Disease Research (CGIDR), Seattle Children's Research Institute, Seattle, Washington 98109, USA.ORCID 0000-0001-9736-9901
Suzanne M McDermottCenter for Global Infectious Disease Research (CGIDR), Seattle Children's Research Institute, Seattle, Washington 98109, USA.ORCID 0000-0003-2158-1695
Jason CarnesCenter for Global Infectious Disease Research (CGIDR), Seattle Children's Research Institute, Seattle, Washington 98109, USA.ORCID 0000-0001-7302-1935
Isaac LewisCenter for Global Infectious Disease Research (CGIDR), Seattle Children's Research Institute, Seattle, Washington 98109, USA.
Maxwell TracyCenter for Global Infectious Disease Research (CGIDR), Seattle Children's Research Institute, Seattle, Washington 98109, USA.
Kenneth D StuartCenter for Global Infectious Disease Research (CGIDR), Seattle Children's Research Institute, Seattle, Washington 98109, USA ken.stuart@seattlechildrens.org.ORCID 0000-0002-4064-9758

Funding

MITOCHONDRIAL DNA OF NORMAL AND MUTANT TRYPANOSOMESR01AI014102 · NIAID · SEATTLE CHILDREN'S HOSPITAL · PI KENNETH D STUART · 1985 to 2026
$20.9M
NIAID NIH HHS R01 AI014102
6 · The paper itself

Abstract

The gRNA directed U-insertion and deletion editing of mitochondrial mRNAs that is essential in different life-cycle stages for the protozoan parasite

Indexed as

RNATrypanosoma brucei bruceiMutationProtozoan ProteinsRNA EditingRNA, ProtozoanProtozoan ProteinsRNARNA, ProtozoanC2H2 zinc-fingerintrinsically disordered regionOB-foldRNA editingTrypanosoma brucei

Identifiers

PMID37474258
PMCPMC10578492

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.