Evidence map›Paper›PMID 37474902›Full record

ArticleBMC neuroscience2023

Hydrogen alleviated cognitive impairment and blood‒brain barrier damage in sepsis-associated encephalopathy by regulating ABC efflux transporters in a PPARα-dependent manner.

Yuanyuan Bai, Wen Mi, Xiaoyin Meng, Beibei Dong, Yi Jiang, Yuechun Lu, Yonghao Yu

Open access · goldAbstract read
In one paragraph

Article in BMC neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Yuanyuan Bai *Department of Anesthesiology, Tianjin Institute of Anesthesiology, Tianjin Medical University General Hospital, No. 154 Anshan Road, Heping District, Tianjin, 300052, PR China.
Wen Mi *Department of Anesthesiology, Tianjin Baodi Hospital, Baodi Clinical College of Tianjin Medical University, Tianjin, 301800, China.
Xiaoyin Meng *Department of Gynecology and Obstetrics, Tianjin Medical University General Hospital, Tianjin, 300052, China.
Beibei DongDepartment of Anesthesiology, Tianjin Institute of Anesthesiology, Tianjin Medical University General Hospital, No. 154 Anshan Road, Heping District, Tianjin, 300052, PR China.
Yi JiangDepartment of Anesthesiology, Tianjin Institute of Anesthesiology, Tianjin Medical University General Hospital, No. 154 Anshan Road, Heping District, Tianjin, 300052, PR China.
Yuechun LuDepartment of Anesthesiology, The Second Hospital of Tianjin Medical University, Tianjin, 300211, China. luyuechun@sina.com.
Yonghao YuDepartment of Anesthesiology, Tianjin Institute of Anesthesiology, Tianjin Medical University General Hospital, No. 154 Anshan Road, Heping District, Tianjin, 300052, PR China. yyu@tmu.edu.cn.
Tianjin Medical University General Hospital · CNSecond Hospital of Tianjin Medical University · CNTianjin Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hydrogen (H

Indexed as

Cognitive DysfunctionSepsis-Associated EncephalopathyAnimalsATP-Binding Cassette TransportersATP Binding Cassette Transporter, Subfamily G, Member 2Blood-Brain BarrierDimethyl SulfoxideEndothelial CellsHydrogenMiceNeoplasm ProteinsOccludinPPAR alphaATP-Binding Cassette TransportersATP Binding Cassette Transporter, Subfamily G, Member 2Dimethyl SulfoxideHydrogenNeoplasm ProteinsOccludinPPAR alphaABC efflux transportersBlood‒brain barrierPeroxisome proliferator-activated receptorsSepsis-associated encephalopathy

Identifiers

PMID37474902
PMCPMC10360271
OpenAlexW4384925461

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.