Evidence map›Paper›PMID 37476303›Full record

ArticleHemaSphere2023

Application of IPSET-thrombosis in 1366 Patients Prospectively Followed From the Spanish Registry of Essential Thrombocythemia.

Alberto Alvarez-Larrán, Beatriz Cuevas, Patricia Velez, Soledad Noya, Gonzalo Caballero-Navarro, Francisca Ferrer-Marín, Sara Carbonell, Manuel Pérez-Encinas, María Teresa Gómez-Casares, Raúl Pérez-López and 16 more

Open access · goldAbstract read
In one paragraph

Article in HemaSphere, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors at 20 institutions in 1 country.

Alberto Alvarez-LarránHospital Clínic Barcelona, Spain.
Beatriz CuevasHospital Universitario de Burgos, Spain.
Patricia VelezHospital de Mar, Barcelona, Spain.
Soledad NoyaComplexo Hospitalario Universitario de A Coruña, Spain.
Gonzalo Caballero-NavarroHospital Miguel Servet, Zaragoza, Spain.
Francisca Ferrer-MarínHospital Morales Messeguer, CIBERER, UCAM, IMIB, Murcia, Spain.
Sara CarbonellHospital Clínic Barcelona, Spain.
Manuel Pérez-EncinasHospital Clínico Universitario de Santiago de Compostela, Spain.
María Teresa Gómez-CasaresHospital Doctor Negrín, Las Palmas de Gran Canaria, Spain.
Raúl Pérez-LópezHospital Virgen de la Arrixaca, Murcia, Spain.
Elena MagroHospital Príncipe de Asturias, Alcalá de Henares, Spain.
Ana MoretóHospital de Cruces, Barakaldo, Spain.
Irene Pastor-GalánHospital Clínico Universitario, Valencia, Spain.
Anna AngonaHospital Doctor Josep Trueta, Girona, Spain.
María Isabel Mata-VázquezHospital Costa del Sol, Marbella, Spain.
Lucía Guerrero-FernándezComplejo Asistencial de Palencia, Spain.
José María GuerraHospital Son Llatzer, Palma de Mallorca, Spain.
Gonzalo Carreño-TarragonaHospital Universitario 12 de octubre, Madrid, Spain.
Laura FoxHospital Universitario Vall d'Hebron, Barcelona, Spain.
Ilda MurilloHospital General San Jorge, Huesca, Spain.
Valentín García-GutiérrezHospital Universitario Ramón y Cajal, IRYCIS, Madrid, Spain.
Elvira MoraHospital Universitario y Politécnico La Fe, Valencia, Spain.
Ruth StuckeyHospital Virgen de la Arrixaca, Murcia, Spain.
Eduardo Arellano-RodrigoHospital Clínic Barcelona, Spain.
Juan Carlos Hernández-BoludaHospital Clínico Universitario, Valencia, Spain.
Arturo PereiraHospital Clínic Barcelona, Spain.
Hospital Clínic de Barcelona · ESCentre for Biomedical Network Research on Rare Diseases · ESHospital Clínico Universitario de Valencia · ESHospital Universitario Virgen de la Arrixaca · ESComplejo Asistencial Universitario de Palencia · ESComplejo Hospitalario Universitario de Santiago · ESComplexo Hospitalario Universitario A Coruña · ESHospital Costa del Sol · ESHospital de Cruces · ESHospital Del Mar · ESHospital General San Jorge · ESHospital Universitari de Girona Doctor Josep Trueta · ESHospital Universitari i Politècnic La Fe · ESHospital Universitario 12 De Octubre · ESHospital Universitario de Burgos · ESHospital Universitario de Gran Canaria Doctor Negrín · ESHospital Universitario Miguel Servet · ESHospital Universitario Príncipe de Asturias · ESInstituto Ramón y Cajal de Investigación Sanitaria · ESVall d'Hebron Hospital Universitari · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The International Prognostic Score of thrombosis in Essential Thrombocythemia (IPSET-thrombosis) and its revised version have been proposed to guide thrombosis prevention strategies. We evaluated both classifications to prognosticate thrombosis in 1366 contemporary essential thrombocythemia (ET) patients prospectively followed from the Spanish Registry of ET. The cumulative incidence of thrombosis at 10 years, taking death as a competing risk, was 11.4%. The risk of thrombosis was significantly higher in the high-risk IPSET-thrombosis and high-risk revised IPSET-thrombosis, but no differences were observed among the lower risk categories. Patients allocated in high-risk IPSET-thrombosis (subdistribution hazard ratios [SHR], 3.7 [95% confidence interval, CI, 1.6-8.7]) and high-risk revised IPSET-thrombosis (SHR, 3.2 [95% CI, 1.4-7.45]) showed an increased risk of arterial thrombosis, whereas both scoring systems failed to predict venous thrombosis. The incidence rate of thrombosis in intermediate risk revised IPSET-thrombosis (aged >60 years,

Identifiers

PMID37476303
PMCPMC10356121
OpenAlexW4384697225

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.