ArticleJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2023
U-shaped association between sleep duration and the risk of respiratory diseases mortality: a large prospective cohort study from UK Biobank.
Article in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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5 citing papers in PubMed, 8 citations in OpenAlex.
- Association between sleep duration and chronic lung diseases among Chinese middle-aged and older adults: A cross-sectional study.PloS one · 2026Article
- Non-linear association of sleep duration with osteoarthritis among U.S. middle-aged and older adults.BMC public health · 2024Article
- Preliminary Evidence of Sleep Improvements Following Psilocybin Administration, and their Involvement in Antidepressant Therapeutic Action.Current psychiatry reports · 2024Review
- Influence of race and age in sleep duration and mortality relationship among adults in the United States: results from the 2004 NHIS-NDI record linkage study.Sleep and biological rhythms · 2024Article
- Flatten the curve: bending the trajectory of respiratory disease-related mortality.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2023Article
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3 authors at 1 institution in 1 country.
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Abstract
STUDY
objectivesOur cohort study aimed to study the association between sleep duration and risk of mortality due to respiratory diseases.
methodsWe included 498,200 participants from UK Biobank (2006-2021). We classified sleep duration as short sleep duration (< 7 hours), long sleep duration (> 9 hours for adults, > 8 hours for older adults), and midrange sleep duration (7-9 hours). We used the Cox proportional hazards model and restricted cubic spline analysis to explore the association between sleep duration and respiratory diseases mortality.
resultsDuring a median follow-up of 12.49 years, 2,477 deaths due to respiratory diseases were recorded, of which 1,099 were deaths due to chronic lower respiratory diseases. Cox models with penalized splines showed U-shaped associations of sleep duration with mortality due to total respiratory diseases and chronic lower respiratory diseases. Compared with midrange sleep duration, short sleep duration was associated with 14% higher risk of total respiratory diseases mortality (hazard ratio = 1.14; 95% confidence interval: 1.04, 1.25), and long sleep duration was associated with 35% higher risk of total respiratory diseases mortality (hazard ratio = 1.35; 95% confidence interval: 1.19, 1.55), after adjustment of baseline characteristics, health status, and lifestyle habits. Similarly, the hazard ratios for chronic lower respiratory diseases mortality were 1.20 (95% confidence interval: 1.04, 1.38) and 1.44 (95% confidence interval: 1.19, 1.74), respectively.
conclusionsThere was a U-shaped association between sleep duration and respiratory diseases mortality. Appropriate sleep duration may improve the progress of respiratory diseases. CITATION: Du M, Liu M, Liu J. U-shaped association between sleep duration and the risk of respiratory diseases mortality: a large prospective cohort study from UK Biobank.
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