Evidence map›Paper›PMID 37483435›Full record

ArticleFrontiers in neurology2023

Identification of key potassium channel genes of temporal lobe epilepsy by bioinformatics analyses and experimental verification.

Lin-Ming Zhang, Ling Chen, Yi-Fei Zhao, Wei-Mei Duan, Lian-Mei Zhong, Ming-Wei Liu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Lin-Ming ZhangDepartment of Neurology, The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China.
Ling ChenDepartment of Neurology, The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China.
Yi-Fei ZhaoDepartment of Neurology, The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China.
Wei-Mei DuanDepartment of Neurology, The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China.
Lian-Mei ZhongDepartment of Neurology, The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China.
Ming-Wei LiuDepartment of Emergency, The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China.
Kunming Medical University · CNFirst Affiliated Hospital of Kunming Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

One of the most prevalent types of epilepsy is temporal lobe epilepsy (TLE), which has unknown etiological factors and drug resistance. The detailed mechanisms underlying potassium channels in human TLE have not yet been elucidated. Hence, this study aimed to mine potassium channel genes linked to TLE using a bioinformatic approach. The results found that Four key TLE-related potassium channel genes (TERKPCGs) were identified: potassium voltage-gated channel subfamily E member (

Indexed as

bioinformatics analysespotassium channel genestarget drugstemporal lobe epilepsyWGCNA

Identifiers

PMID37483435
PMCPMC10361730
OpenAlexW4383558427

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.