Evidence map›Paper›PMID 37484159›Full record

ArticleIranian journal of public health2023

Comprehensive Analysis of Differential Gene Expression and Correlated Immune Infiltration in Bladder Cancer.

Xiao Xiao, Junxiong Peng, Yong Chen, Xingshan Lu, Wei Sun, Weizhong Xiao, Mengjuan Yuan, Xiaolan Huang

Open access · goldAbstract read
In one paragraph

Article in Iranian journal of public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Xiao XiaoUrology Department, Chongqing University Fuling Hospital, Chongqing, 408000, PR China.
Junxiong PengUrology Department, Chongqing University Fuling Hospital, Chongqing, 408000, PR China.
Yong ChenUrology Department, Chongqing University Fuling Hospital, Chongqing, 408000, PR China.
Xingshan LuUrology Department, Chongqing University Fuling Hospital, Chongqing, 408000, PR China.
Wei SunUrology Department, Chongqing University Fuling Hospital, Chongqing, 408000, PR China.
Weizhong XiaoUrology Department, Chongqing University Fuling Hospital, Chongqing, 408000, PR China.
Mengjuan YuanUrology Department, Chongqing University Fuling Hospital, Chongqing, 408000, PR China.
Xiaolan HuangUrology Department, Chongqing University Fuling Hospital, Chongqing, 408000, PR China.
Chongqing University · CNFuling Center Hospital of Chongqing · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Bladder cancer (BCa) is one of the most common urinary tract malignancies. Our study aimed to provide promising biomarkers for BCa screening and prognosis. Methods: BCa samples were obtained from Gene Expression Omnibus (GEO) datasets. Differentially expressed genes (DEGs) were analysed by GO/KEGG analysis. Univariate Cox hazard analysis and Kaplan Meier Curve clarified the relevance of DEGs and survival. Receiver operating characteristic (ROC) curve showed the discrimination ability of DEGs in BCa patient outcome prediction. RT-PCR was used to validate gene expression. Results: Overall, 61 common up regulated and 170 common down-regulated genes in BCa were obtained. DEGs were mainly enriched in proliferation and metastasis processes. Conclusion:

Indexed as

BiomarkerBladder cancerDifferentially expressed genes (DEGs)Immune infiltrationNetwork analysis

Identifiers

PMID37484159
PMCPMC10362833
OpenAlexW4381995942

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.