Evidence mapPaperPMID 37485354Full record

ArticleiScience2023

Moderate-intensity endurance training improves late phase β-cell function in adults with type 2 diabetes.

Hui Zhang, Laura K Simpson, Nicholas P Carbone, Michael F Hirshman, Pasquale Nigro, Maria Vamvini, Laurie J Goodyear, Roeland J W Middelbeek

Open access · goldAbstract read
In one paragraph

Article in iScience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Hui ZhangSection on Integrative Physiology and Metabolism, Joslin Diabetes Center, Boston, MA 02215, USA.
Laura K SimpsonSection on Integrative Physiology and Metabolism, Joslin Diabetes Center, Boston, MA 02215, USA.
Nicholas P CarboneSection on Integrative Physiology and Metabolism, Joslin Diabetes Center, Boston, MA 02215, USA.
Michael F HirshmanSection on Integrative Physiology and Metabolism, Joslin Diabetes Center, Boston, MA 02215, USA.
Pasquale NigroSection on Integrative Physiology and Metabolism, Joslin Diabetes Center, Boston, MA 02215, USA.
Maria VamviniSection on Integrative Physiology and Metabolism, Joslin Diabetes Center, Boston, MA 02215, USA.
Laurie J GoodyearSection on Integrative Physiology and Metabolism, Joslin Diabetes Center, Boston, MA 02215, USA.
Roeland J W MiddelbeekSection on Integrative Physiology and Metabolism, Joslin Diabetes Center, Boston, MA 02215, USA.
Joslin Diabetes Center · US

Funding

PILOT STUDY--SECRETORY TARGETING IN PANCREATIC B CELLSP30DK036836 · JOSLIN DIABETES CENTER · 1986 to 2025
$12.1M
Novel Mechanisms of Exercise Training Effects on Glucose HomeostasisR01DK099511 · NIDDK · JOSLIN DIABETES CENTER · 2022 to 2025
$2.0M
NIDDK NIH HHS P30 DK036836NIDDK NIH HHS R01 DK099511
6 · The paper itself

Abstract

Physical activity is important for type 2 diabetes treatment, yet the underlying mechanisms for these beneficial effects of exercise are not fully understood. Here, we investigated the effects of exercise training on biphasic β-cell insulin secretory function, a key factor regulating blood glucose. Adults with type 2 diabetes (7F/3M, age 49 ± 5 years, BMI 30 ± 3 kg/m

Indexed as

Human metabolismKinesiology

Identifiers

PMID37485354
PMCPMC10362261
OpenAlexW4382468014

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.