Evidence map›Paper›PMID 37492809›Full record

ArticleCureus2023

Transcriptional Differences in Identical Twins With Different Reproductive Capacities: A Case Report.

Katherine Campbell, Alexandra Dullea, Christian Ramsoomair, Kyle Schuppe, Armin Ghomeshi, Kajal Khodamoradi, Himanshu Arora, Carolina Jorgez, Ranjith Ramasamy

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Katherine CampbellUrology, University of Miami Desai Sethi Urology Institute, Miami, USA.
Alexandra DulleaUrology, University of Miami Desai Sethi Urology Institute, Miami, USA.
Christian RamsoomairUrology, University of Miami Desai Sethi Urology Institute, Miami, USA.
Kyle SchuppeMedicine, Washington State University Elson S. Floyd College of Medicine, Spokane, USA.
Armin GhomeshiPsychiatry, Florida International University, Herbert Wertheim College of Medicine, Miami, USA.
Kajal KhodamoradiUrology, University of Miami Miller School of Medicine, Miami, USA.
Himanshu AroraUrology, University of Miami, Miami, USA.
Carolina JorgezUrology, Baylor College of Medicine, Houston, USA.
Ranjith RamasamyUrology, University of Miami, Miami, USA.

Funding

Medical Scientist Training ProgramT32GM145462 · NIGMS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI ALESSIA FORNONI, Daniel Jon Liebl · 2022 to 2026
$3.9M
6 · The paper itself

Abstract

Disorders of sperm production can be classified quantitatively as oligospermia (low sperm count) or azoospermia (no sperm during ejaculation). Numerous genes have been implicated in spermatogenesis. We describe a case of two identical twins who presented with different reproductive capabilities. One brother was infertile due to azoospermia, and the other, although oligospermic, previously naturally fathered a child. They were found to have differential gene expression based on RNA sequencing analysis. In the man with azoospermia, we found elevated

Indexed as

azoospermiacase reporte2f1geneticshoxinfertility

Identifiers

PMID37492809
PMCPMC10363651

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.