Evidence map›Paper›PMID 37493259›Full record

ArticleThe British journal of radiology2023

Cumulative radiation exposure from radiological imaging in patients with Hodgkin and diffuse large b-cell lymphoma not submitted to radiotherapy.

Marco Brambilla, Roberta Matheoud, Gloria Margiotta-Casaluci, Barbara Cannillo, Andrea D'Alessio, Chiara Siciliano, Alessandro Carriero, Gianluca Gaidano

Abstract read
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Article in The British journal of radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Marco BrambillaMedical Physics Department, University Hospital "Maggiore della Carità", Novara, Italy.
Roberta MatheoudMedical Physics Department, University Hospital "Maggiore della Carità", Novara, Italy.
Gloria Margiotta-CasaluciDivision of Hematology, Department of Translational Medicine, University of Eastern Piedmont, Novara, Italy.
Barbara CannilloMedical Physics Department, University Hospital "Maggiore della Carità", Novara, Italy.
Andrea D'AlessioMedical Physics Department, University Hospital "Maggiore della Carità", Novara, Italy.
Chiara SicilianoRadiology Department, University Hospital "Maggiore della Carità", Hodgkin, Italy.
Alessandro CarrieroRadiology Department, University Hospital "Maggiore della Carità", Hodgkin, Italy.
Gianluca GaidanoDivision of Hematology, Department of Translational Medicine, University of Eastern Piedmont, Novara, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess the cumulated exposure to radiation due to imaging in Hodgkin (HL) and diffuse large B-cell (DLBCL) lymphoma patients who were not submitted to radiotherapy.

methodsThe study population included 51 and 83 adult patients with HL and DLBCL, with a follow-up duration >1 year. The cumulated exposure was expressed using patient-specific data as cumulated effective dose (CED).

resultsFifty-one HL patients (median age 47 years) were followed for a median of 3.5 years. The median total CED per subject was 104 mSv. CT and PET/CT examinations accounted for 75 and 25% of the total CED, respectively. 26 patients (49%) had a total CED ≥ 100 mSv and the maximum CED was 302 mSv. Eighty-three DLBCL patients (median age 66 years) were followed for a median of 3.7 years. The median total CED per subject over the study period was 134 mSv. CT and PET/CT for 86% and 13% of the total CED, respectively. 56 patients (67%) had a total CED ≥100 mSv. The maximum CED was 557 mSv.

conclusionOur study demonstrated the large number of imaging procedures performed for patients with lymphoma. Overall, 61% of the patients accrued a CED ≥ 100 mSv. Imaging policies were only in a partial agreement with current international guidelines. ADVANCES IN KNOWLEDGE: The cumulated exposure radiation exposure may be of concern in HL patients and the contribution of CT procedures to the total CED is significant. The standardisation of clinical guidelines for managing patients with lymphoma is warranted.

Indexed as

Lymphoma, Large B-Cell, DiffuseRadiation ExposureAdultAgedHumansMiddle AgedPositron Emission Tomography Computed TomographyRadiation DosageTomography, X-Ray Computed

Identifiers

PMID37493259
PMCPMC10461276

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.