Evidence map›Paper›PMID 37493721›Full record

ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2024

Analysis of intracranial pressure waveform using a non-invasive method in individuals with craniosynostosis.

Michele Madeira Brandao, Cristiano Tonello, Isabella Parizotto, Luciano Brandao Machado, Nivaldo Alonso

Abstract read
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In one paragraph

Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Surgery for isolated sagittal synostosis: a neuro-developmental necessity or an isolated cosmetic challenge? Mini-survey and literature review.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026
    Review
  2. Cognitive and neuropsychomotor development in craniosynostosis: an evaluation of the most affected functions.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026
    Observational
  3. Non-invasive intracranial pressure analysis in craniosynostosis: an intriguing insight.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Michele Madeira BrandaoHospital of Rehabilitation of Craniofacial Anomalies of the University of São Paulo, São Paulo, Bauru, Brazil. dramichele@usp.br.ORCID 0000-0001-5919-0759
Cristiano TonelloHospital of Rehabilitation of Craniofacial Anomalies of the University of São Paulo, São Paulo, Bauru, Brazil.ORCID 0000-0002-0881-416X
Isabella ParizottoHospital of Rehabilitation of Craniofacial Anomalies of the University of São Paulo, São Paulo, Bauru, Brazil.ORCID 0000-0001-6039-9146
Luciano Brandao MachadoHospital of Rehabilitation of Craniofacial Anomalies of the University of São Paulo, São Paulo, Bauru, Brazil.ORCID 0000-0001-6806-4332
Nivaldo AlonsoHospital of Rehabilitation of Craniofacial Anomalies of the University of São Paulo, São Paulo, Bauru, Brazil.ORCID 0000-0003-1532-9610
Universidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeCraniosynostosis can lead to symptoms resulting from cranial compliance (CC) changes and intracranial hypertension (ICH), which may cause cognitive and visual impairment. Non-invasive methods have emerged, including a new device that captures and processes the intracranial pressure waveform (ICPw) by the skull's oscillation. The present study evaluates ICPw obtained non-invasively (NIICPw) in patients with craniosynostosis.

methodsThis prospective, cross-sectional, and descriptive study was conducted at a single center. Patients diagnosed with craniosynostosis and who provided informed consent were included. A US Food and Drug Administration-approved mechanical extensometer device (Brain4Care Corp.) was used to obtain a NIICPw. An ophthalmologist did a point-of-care retinography to check the optic nerve papilla. The P2/P1 ratio and the morphology of the NIICPw were analyzed, as well as the retinography.

resultsThirty-five patients were evaluated, and 42 registers were obtained because seven were assessed before and after the surgery. The two patients who presented papilledema had low CC (NIICPw shape Class 3 or 4). There was a significant association between NIICPw and papilledema.

conclusionThe ratio P2/P1 and the NIICPw morphology provided by a non-invasive monitor are related to CC changes before papilledema occurs. This is especially useful in patients with craniosynostosis because invasive ICP monitoring is not always feasible. Further studies are warranted to establish the clinical utility of NIICPw in patients with craniosynostosis.

Indexed as

CraniosynostosesIntracranial HypertensionPapilledemaCross-Sectional StudiesHumansIntracranial PressureProspective StudiesCraniosynostosisIntracranial hypertensionIntracranial pressurePapilledema

Identifiers

PMID37493721
OpenAlexW4385264783

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.