ArticleNature2023
Mammary duct luminal epithelium controls adipocyte thermogenic programme.
Open access · greenAbstract read
In one paragraph
Article in Nature, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed, 18 citations in OpenAlex.
- Review
- Article
- Commentary: Mammokine directs beige adipocytes to reserve energy for milk production in breast.Acta pharmaceutica Sinica. B · 2024Article
- Review
- Uncoupling protein 1-driven Cre (bioRxiv : the preprint server for biology · 2023Article
- Mesenchymal stromal cells as conductors of adipose tissue remodeling.Genes & development · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
23 authors at 5 institutions in 2 countries.
Sanil Patel *Diabetes, Obesity, and Metabolism Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID 0009-0002-7874-1063
Njeri Z R Sparman *Diabetes, Obesity, and Metabolism Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Douglas Arneson *Department of Integrative Biology and Physiology and Bioinformatics Interdepartmental Program, University of California, Los Angeles, CA, USA.
Alexandra Alvarsson *Diabetes, Obesity, and Metabolism Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Luís C SantosDiabetes, Obesity, and Metabolism Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Samuel J DuesmanDepartment of Psychiatry and Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Alessia CentonzeLaboratory of Stem Cells and Cancer, Université Libre de Bruxelles (ULB), Brussels, Belgium.
Ephraim HathawayDiabetes, Obesity, and Metabolism Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID 0009-0006-7048-4145
In Sook AhnDepartment of Integrative Biology and Physiology and Bioinformatics Interdepartmental Program, University of California, Los Angeles, CA, USA.
Graciel DiamanteDepartment of Integrative Biology and Physiology and Bioinformatics Interdepartmental Program, University of California, Los Angeles, CA, USA.
Ingrid CelyDepartment of Integrative Biology and Physiology and Bioinformatics Interdepartmental Program, University of California, Los Angeles, CA, USA.
Chung Hwan ChoDiabetes, Obesity, and Metabolism Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID 0009-0003-8977-5274
Noble Kumar TalariDepartment of Pharmacology and Systems Physiology, University of Cincinnati College of Medicine, Cincinnati, OH, USA.ORCID 0000-0001-9744-0771
Abha K RajbhandariDepartment of Psychiatry and Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID 0000-0002-5596-8735
Leigh GoedekeDiabetes, Obesity, and Metabolism Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Peng WangDiabetes, Obesity, and Metabolism Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Atul J ButteBakar Computational Health Sciences Institute, University of California, San Francisco, CA, USA.ORCID 0000-0002-7433-2740
Cédric BlanpainLaboratory of Stem Cells and Cancer, Université Libre de Bruxelles (ULB), Brussels, Belgium.ORCID 0000-0002-4028-4322
Karthickeyan Chella KrishnanDepartment of Pharmacology and Systems Physiology, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Aldons J LusisDepartment of Medicine, Division of Cardiology, and Department of Human Genetics, University of California, Los Angeles, CA, USA.ORCID 0000-0001-9013-0228
Sarah A StanleyDiabetes, Obesity, and Metabolism Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID 0000-0002-0253-2663
Xia YangDepartment of Integrative Biology and Physiology and Bioinformatics Interdepartmental Program, University of California, Los Angeles, CA, USA.
Prashant RajbhandariDiabetes, Obesity, and Metabolism Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA. prashant.rajbhandari@mssm.edu.ORCID 0000-0002-8146-3861
Icahn School of Medicine at Mount Sinai · USUniversity of California, Los Angeles · USUniversité Libre de Bruxelles · BEUniversity of California, San Francisco · USUniversity of Cincinnati Medical Center · US
Funding
Translational Research CoreP30DK020541 · NIDDK · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI STREAMSON C CHUA · 2015 to 2026
$27.7MSex Differences in the Metabolic SyndromeU54DK120342 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI REUE, KAREN · 2018 to 2022
$7.6MSystems Genetics Dissection of Non-alcoholic SteatohepatitisR01DK117850 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Aldons Jake Lusis · 2019 to 2026
$4.6MRemote Electromagnetic Control of Neural Activity for Treatment of Parkinson's DiseaseR01NS097184 · NINDS · ROCKEFELLER UNIVERSITY · PI DORDICK, JONATHAN S., FRIEDMAN, JEFFREY M · 2016 to 2020
$3.4MNeural control of pancreatic endocrine function in obesity and diabetesR01DK124461 · NIDDK · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI STANLEY, SARAH AMY · 2021 to 2024
$2.4MSystems-based approaches for investigating tissue communication during exerciseU01AG070959 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI HEVENER, ANDREA L, LUSIS, ALDONS JAKE · 2020 to 2022
$1.2MRemote Modulation of the Peripheral Nervous SystemOT2OD024912 · OD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI STANLEY, SARAH AMY · 2017 to 2019
$1.1MCellular and molecular mechanisms of diabetic atherosclerosisR00HL150234 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI GOEDEKE, LEIGH · 2022 to 2024
$747kInterleukin-10 Signaling in Adipose Tissue Thermogenesis and Energy expenditureR00DK114571 · NIDDK · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI RAJBHANDARI, PRASHANT · 2019 to 2021
$744kInvestigating the sex-specific roles of PKLR and CHCHD6 in insulin resistance and NAFLDR00DK120875 · NIDDK · UNIVERSITY OF CINCINNATI · PI CHELLA KRISHNAN, KARTHICKEYAN · 2021 to 2023
$737kNHLBI NIH HHS R00 HL150234NIA NIH HHS U01 AG070959NIDDK NIH HHS P30 DK020541NIDDK NIH HHS R00 DK114571NIDDK NIH HHS R00 DK120875NIDDK NIH HHS R01 DK117850NIDDK NIH HHS R01 DK124461NIDDK NIH HHS U54 DK120342NIH HHS OT2 OD024912NINDS NIH HHS R01 NS097184
Abstract
Sympathetic activation during cold exposure increases adipocyte thermogenesis via the expression of mitochondrial protein uncoupling protein 1 (UCP1)
Indexed as
AdipocytesAdipose Tissue, WhiteEpitheliumMammary Glands, AnimalThermogenesisAnimalsCold TemperatureEnergy MetabolismFemaleLipocalin-2MaleMiceOxidation-ReductionSex CharacteristicsSympathetic Nervous SystemUncoupling Protein 1Lcn2 protein, mouseLipocalin-2Ucp1 protein, mouseUncoupling Protein 1
Identifiers
What Socratic holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.