Evidence map›Paper›PMID 37498159›Full record

Trial reportJournal of the International Society of Sports Nutrition2023

Effects of maslinic acid supplementation on exercise-induced inflammation and oxidative stress in water polo athletes: A randomized, double-blind, crossover, and placebo-controlled trial.

Takanaga Shirai, Kanae Myoenzono, Eiskue Kawai, Yuki Yamauchi, Keito Suzuki, Seiji Maeda, Hideki Takagi, Tohru Takemasa

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of the International Society of Sports Nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Role of maslinic acid in ischemia-reperfusion-induced testicular injury in rats.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2026
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Takanaga ShiraiUniversity of Tsukuba, Faculty of Health and Sport Sciences, Tsukuba, Ibaraki, Japan.
Kanae MyoenzonoUniversity of Tsukuba, Faculty of Health and Sport Sciences, Tsukuba, Ibaraki, Japan.
Eiskue KawaiUniversity of Tsukuba, Faculty of Health and Sport Sciences, Tsukuba, Ibaraki, Japan.
Yuki YamauchiUniversity of Tsukuba, Tsukuba Life Science Innovation Program (T-LSI), Tsukuba, Ibaraki, Japan.
Keito SuzukiNippn Corporation, Central Research Laboratory Innovation Center, Atsugi, Kanagawa, Japan.
Seiji MaedaUniversity of Tsukuba, Faculty of Health and Sport Sciences, Tsukuba, Ibaraki, Japan.
Hideki TakagiUniversity of Tsukuba, Faculty of Health and Sport Sciences, Tsukuba, Ibaraki, Japan.
Tohru TakemasaUniversity of Tsukuba, Faculty of Health and Sport Sciences, Tsukuba, Ibaraki, Japan.ORCID 0000-0002-9591-2250
University of Tsukuba · JPInternational Budo University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOlive fruit is rich in bioactive pentacyclic triterpenoids, primarily maslinic acid (MA). Previous studies have demonstrated that MA exhibits anti-inflammatory and anti-oxidative effects; however, it is unclear whether MA intake during training inhibits perceptual fatigue and muscle soreness in athletes. This study analyzed the effects of MA supplementation during athletic training on perceptual fatigue and muscle soreness.

methodsThis randomized, double-blind, cross-over, and placebo-controlled trial involved 12 young, healthy male water polo athletes. After daily training for seven days, they ingested either olive fruit extract, containing 60 mg/day MA, or a placebo. We measured perceptual fatigue and muscle soreness during the intervention using a visual analog scale and inflammatory and oxidative stress-related proteins.

resultsPerceptual fatigue and muscle soreness and the area under the curve during the training period were significantly lower (main effect of MA;

conclusionThese findings suggest that MA intake not only reduces perceptual fatigue and muscle soreness but also decreases inflammation and oxidative stress in the blood and skeletal muscle.

Indexed as

MyalgiaWater SportsAthletesDietary SupplementsDouble-Blind MethodFatigueHumansInflammationMaleMuscle, SkeletalOleanolic AcidOxidative Stressmaslinic acidOleanolic AcidfatigueinflammationMaslinic acidmuscle sorenesswater polo athletes

Identifiers

PMID37498159
PMCPMC10375926
OpenAlexW4385295737

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.